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Ethylbenzene (100-41-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020596

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Ethylbenzene (100-41-4).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Ethylbenzene (100-41-4).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Ethylbenzene (100-41-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Ethylbenzene (100-41-4).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Ethylbenzene (100-41-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-466 Toxicology and Carcinogenesis Studies of Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
TOX-10 Toxicity Studies of Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1Mice (Inhalation Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C56393) of Ethylbenzene (100-41-4) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C56393) of Ethylbenzene (100-41-4) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C56393B) of Ethylbenzene (100-41-4) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C56393B) of Ethylbenzene (100-41-4) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Ethylbenzene (100-41-4) in Micronucleus Study A97698 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethylbenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 450636
Summary Data

Other NTP Studies

Toxicokinetic Evaluation (S0636) of ethylbenzene (DTXSID3020596) in Rat and Mouse
Data

NTP Data Collections