Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Ethylene glycol (107-21-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8020597

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Ethylene glycol (107-21-1).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Ethylene glycol (107-21-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Ethylene glycol (107-21-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Ethylene glycol (107-21-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-413 Toxicology and Carcinogenesis Studies of Ethylene Glycol (CASRN 107-21-1) in B6C3F1 Mice (Feed Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Final Report on the Developmental Stages of the CD Rat Skeleton: Part II: Development After Maternal Exposure to Ethylene Glycol
Final Report on the Developmental Toxicity of Ethylene Glycol in New Zealand White Rabbits
Final Report on the Developmental Toxicity of Ethylene Glycol in New Zealand White Rabbits
Final Report: Teratologic Evaluation of Ethylene Glycol Administered to CD Rats on Gestational Days 6 through 15.
Teratologic Evaluation of Ethylene Glycol Administered to CD-1 Mice on Gestational Days 6 through 15
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C00920A) of Ethylene Glycol (107-21-1) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Ethylene Glycol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 195794
Summary Data

Other NTP Studies

Prenatal Developmental Toxicity Study (TER84073) of Ethylene Glycol (107-21-1) in Swiss CD-1 Mice Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER89126) of Ethylene Glycol (107-21-1) in CD Rats Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER90005) of Ethylene Glycol (107-21-1) in New Zealand White Rabbits Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER90072) of Ethylene Glycol (107-21-1) in Sprague-Dawley Rats Exposed via Gavage
Individual and Summary Data

DTT Data Collections