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2-Butoxyethanol (111-76-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1024097


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2-Butoxyethanol (111-76-2).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 2-Butoxyethanol (111-76-2).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2-Butoxyethanol (111-76-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Butoxyethanol (111-76-2).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. 2-Butoxyethanol (111-76-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
TOX-26 Toxicity Studies of Ethylene Glycol Ethers 2-Methoxyethanol, 2-Ethoxyethanol, 2-Butoxyethanol (CASRNs 109-86-4, 110-80-5, 111-76-2) Administered in Drinking Water to F344/N Rats and B6C3F1Mice
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Final Report - Teratologic Evaluation of Ethylene Glycol Monobutyl Ether Administered to Fischer-344 Rats on Either Gestational Days 9 through 11 or Days 11 through 13

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C62077) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344 Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C62077B) of NTP-88 Diet Study (EGMBE) (111-76-2) in F344 Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C62077B) of NTP-88 Diet Study (EGMBE) (111-76-2) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C62077) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077C) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077B) of NTP-88 Diet Study (EGMBE) (111-76-2) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C62077) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in B6C3F1 Mice Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077B) of NTP-88 Diet Study (EGMBE) (111-76-2) in B6C3F1 Mice Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C62077D) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in Micronucleus Study A89412 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in Micronucleus Study A96057 in F344 Rats
Genetic Toxicity Evaluation of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 006665
Summary Data

Other NTP Studies


Prenatal Developmental Toxicity Study (TER88076) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats Exposed via Gavage
Prenatal Developmental Toxicity Study (TER88141) of 2-Butoxyethanol (Ethylene Glycol Monobutyl Ether) (111-76-2) in F344/N Rats Exposed via Gavage