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bis(2-Chloroethoxy)methane (111-91-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4023917


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to bis(2-Chloroethoxy)methane (111-91-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to bis(2-Chloroethoxy)methane (111-91-1).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to bis(2-Chloroethoxy)methane (111-91-1).
Bacterial Mutagenicity
View
  • Equivocal
View
  • Positive

Citation Information


NTP. bis(2-Chloroethoxy)methane (111-91-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-536 Toxicology and Carcinogenesis Studies of bis(2-Chloroethoxy)methane (CASRN 111-91-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application. NTP Special Study
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344 Rats Exposed via Topical Application. NTP Special Study
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344 Rats Exposed via Topical Application. NTP Special Study
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application. NTP Special Study
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application. NTP Special Study
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application
Acute Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
Acute Evaluation of the Toxicity (C99028B) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane (111-91-1) in Micronucleus Study A22073 in B6C3F1 Mice
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane (111-91-1) in Micronucleus Study A53820 in F344 Rats
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A20931
Summary Data
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A92025
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0816) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats and B6C3F1 Mice Exposed via Gavage, Intravenous Injection or Topical Application
Toxicokinetic Evaluation (C99028) of Bis 2-Chloroethoxy Methane (111-91-1) in F344/N Rats and B6C3F1 Mice Exposed via Topical Application or Intravenous Injection
Data - bis(2-Chloroethoxy)methane and Thiodiglycolic Acid
Data - bis(2-Chloroethoxy)methane
Data - Thiodiglycolic Acid
Toxicokinetic Evaluation (K08624) of Bis 2-Chloroethoxy Methane (DTXSID4023917) in Rat and Mouse