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TR-536: bis(2-Chloroethoxy)methane (111-91-1)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-536: bis(2-Chloroethoxy)methane (111-91-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-536: bis(2-Chloroethoxy)methane (111-91-1).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-536: bis(2-Chloroethoxy)methane (111-91-1).
Bacterial Mutagenicity
View
  • Positive
View
  • Equivocal

Citation Information


NTP. TR-536: bis(2-Chloroethoxy)methane (111-91-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-536 Toxicology and Carcinogenesis Studies of bis(2-Chloroethoxy)methane (CASRN 111-91-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application
Acute Evaluation of the Toxicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
Acute Evaluation of the Toxicity (C99028B) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in F344/N Rats Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C99028) of bis(2-Chloroethoxy)methane (111-91-1) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane (111-91-1) in Micronucleus Study A22073 in B6C3F1 Mice
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane (111-91-1) in Micronucleus Study A53820 in F344 Rats
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A20931
Summary Data
Genetic Toxicity Evaluation of bis(2-Chloroethoxy)methane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A92025
Summary Data