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2-Hydroxy-4-methoxybenzophenone (131-57-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3022405


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2-Hydroxy-4-methoxybenzophenone (131-57-7).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2-Hydroxy-4-methoxybenzophenone (131-57-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Hydroxy-4-methoxybenzophenone (131-57-7).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Negative
View
  • Negative

Citation Information


NTP. 2-Hydroxy-4-methoxybenzophenone (131-57-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-597 NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2-Hydroxy-4-methoxybenzophenone in Harlan Sprague-Dawley Rats
TOX-21 Toxicity Studies of 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered Topically and in Dosed Feed to F344/N Rats and B6C3F1Mice
DART-05 NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal and Reproductive Performance Assessments in F1 Offspring
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C60957A) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C60957B) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C60957A) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C60957B) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in B6C3F1 Mice Exposed via Topical Application
Evaluation of the Chronic (with Perinatal Exposure) Toxicity and Carcinogenicity (C10260) of 2-Hydroxy-4-methoxybenzophenone (131-57-7 ) in Harlan Sprague-Dawley Rat Exposed via Dosed Feed
Study Tables
Interim of Chronic (with Perinatal Exposure) Study at 3 Months
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C10260) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in B6C3F1/N Mice Exposed via Dosed Feed
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in Micronucleus Study A48127 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 381877
Summary Data
Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 613844
Summary Data
Genetic Toxicity Evaluation of 2-hydroxy-4-methoxybenzophenone (131-57-7) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G10260
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0073) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in F344 Rats Exposed via Gavage Administration, Dermal Application or Intravenous Injection
Modified One Generation (MOG) Dose Range Finding Toxicity Study (MOG002) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Modified One Generation (MOG) Toxicity Study (MOG002B) of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Modified One Generation Study Tables
Modified One Generation Individual Data
Toxicokinetic Evaluation (S0593) of 2-Hydroxy-4-methoxybenzophenone (DTXSID3022405) in Rat and Mouse