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4-Hexylresorcinol (136-77-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020699


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 4-Hexylresorcinol (136-77-6).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 4-Hexylresorcinol (136-77-6).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 4-Hexylresorcinol (136-77-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Hexylresorcinol (136-77-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Hexylresorcinol (136-77-6).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 4-Hexylresorcinol (136-77-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-330 Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Hexylresorcinol (136-77-6) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Hexylresorcinol (136-77-6) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Hexylresorcinol (136-77-6) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Hexylresorcinol (136-77-6) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 4-Hexylresorcinol (136-77-6) in Micronucleus Study A25951 in F344 Rats
Genetic Toxicity Evaluation of 4-Hexylresorcinol (136-77-6) in Micronucleus Study A27137 in B6C3F1 Mice
Genetic Toxicity Evaluation of 4-Hexylresorcinol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 267489
Summary Data
Genetic Toxicity Evaluation of 4-Hexylresorcinol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 948583
Summary Data