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2,4,5-Trimethylaniline (137-17-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9021398

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2,4,5-Trimethylaniline (137-17-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 2,4,5-Trimethylaniline (137-17-7).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,4,5-Trimethylaniline (137-17-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. 2,4,5-Trimethylaniline (137-17-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-160 Bioassay of 2,4,5-Trimethylaniline for Possible Carcinogenicity (CASRN 137-17-7)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4,5-Trimethylaniline (137-17-7) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4,5-Trimethylaniline (137-17-7) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4,5-Trimethylaniline (137-17-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4,5-Trimethylaniline (137-17-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2,4,5-Trimethylaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 175438
Summary Data

NTP Data Collections