t-Butylhydroquinone (1948-33-0)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6020220
Study Results
Chronic Bioassay Level of Evidence
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| Mice | |
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Genetic Toxicology
| Rodent Cytogenetics |
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| CA |
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| Micronucleus - Mice |
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| Mammalian Cell Cytogenetics | |
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| CA | SCE |
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| Bacterial Mutagenicity |
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Publications
TR-459
Toxicology and Carcinogenesis Studies of t-Butylhydroquinone (CASRN 1948-33-0) in F344 Rats and B6C3F1 Mice (Feed Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Study Data
Toxicity and Carcinogenicity Studies
9-Week Evaluation of the Toxicity (C62157) of t-Butylhydroquinone (1948-33-0) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C62157) of t-Butylhydroquinone (1948-33-0) in F344 Rats Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C62157) of t-Butylhydroquinone (1948-33-0) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C62157) of t-Butylhydroquinone (1948-33-0) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C62157) of t-Butylhydroquinone (1948-33-0) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C62157) of t-Butylhydroquinone (1948-33-0) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C62157) of t-Butylhydroquinone (1948-33-0) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C62157) of t-Butylhydroquinone (1948-33-0) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of t-Butylhydroquinone (1948-33-0) in Micronucleus Study A34876 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of t-Butylhydroquinone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 663851
Summary Data
- G06 - Ames Summary Data (182 KB)
Genetic Toxicity Evaluation of t-Butylhydroquinone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A71156
Summary Data
- G06 - Ames Summary Data (158 KB)
Other NTP Studies
2-Week Immunotoxicity Evaluation (IMM87036) of t-Butylhydroquinone (1948-33-0) in Female B6C3F1 Mice Exposed via Gavage
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (14 kB)
- Body Weights (89 kB)
- Hematology (13 kB)
- Host Resistance to B16F10 Melanoma Tumors (4 kB)
- Lymphocyte Proliferation (15 kB)
- Mixed Leukocyte Response (9 kB)
- Natural Killer Activity (10 kB)
- Organ Weights (20 kB)
- Resistance to Infection with Streptococcus Pneumoniae (28 kB)
- Reticulocytes (8 kB)
- Reticuloendothelial System (21 kB)
- Surface Markers (%) (9 kB)
- T-Dependent AB Response Day 4 (13 kB)
- T-Dependent AB Response Day 5 (13 kB)