Urethane (51-79-6)
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity | |
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SLRL | RT |
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Bacterial Mutagenicity |
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Publications
TR-510
Toxicology and Carcinogenesis Studies of Urethane + Ethanol (CASRNs 51-79-6 & 64-17-5) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
TOX-52
Toxicity Studies of Urethane in Drinking Water and Urethane in 5% Ethanol in F344/N Rats and B6C3F1Mice (CASRN 51-79-6)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C00602B) of Urethane (51-79-6) in F344 Rats Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C00602B) of Urethane (51-79-6) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C00602B) of Urethane (51-79-6) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C00602B) of Urethane (51-79-6) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity of Urethane (51-79-6) in Female B6C3F1/NCTR BR (C57BL/6N x C3H/HEN MTV-) Mice Exposed via Dosed Water
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Urethane (51-79-6) in Micronucleus Study A06541 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Urethane (51-79-6) in Micronucleus Study A36432 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Urethane (51-79-6) in Micronucleus Study A44972 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Urethane (51-79-6) in Micronucleus Study A86637 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Urethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 113016
Summary Data
- G06 - Ames Summary Data (129 KB)
Genetic Toxicity Evaluation of Urethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 588195
Summary Data
- G06 - Ames Summary Data (121 KB)
Other NTP Studies
2-Week Immunotoxicity Evaluation (IMM83002) of Urethane (51-79-6) in Female B6C3F1 Mice Exposed via Subcutaneous Injection
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (10 kB)
- Hematology (10 kB)
- T-Dependent AB Response Day 4 (13 kB)
- T-Dependent AB Response Day 5 (13 kB)
- T-Dependent AB Response Day 6 (13 kB)