Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Methyl dopa (555-30-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5023295

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Methyl dopa (555-30-6).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Methyl dopa (555-30-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Methyl dopa (555-30-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Methyl dopa (555-30-6).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Methyl dopa (555-30-6).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Methyl dopa (555-30-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Teratologic Evaluation of Alpha-Methyldopa Administered tp CD-1 Mice on Gestational Days 6 through 17
Teratologic Evaluation of Alpha-Methyldopa Administered to CD Rats on Gestational Days 6-20
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Methyl Dopa (555-30-6) in Micronucleus Study A34520 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Methyl Dopa in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 515921
Summary Data

Other NTP Studies

Prenatal Developmental Toxicity Study (TER85090) of Methyl Dopa (555-30-6) in Sprague-Dawley Rats Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER86091) of Methyl Dopa (555-30-6) in Swiss CD-1 Mice Exposed via Gavage
Individual and Summary Data

DTT Data Collections