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7,12-Dimethylbenzanthracene (57-97-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020510


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 7,12-Dimethylbenzanthracene (57-97-6).
Micronucleus - Mice
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  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 7,12-Dimethylbenzanthracene (57-97-6).
Mammalian Cell Mutagenicity
View
  • Positive
View
  • Positive
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 7,12-Dimethylbenzanthracene (57-97-6).
Drosophila Germ Cell Mutagenicity
SLRL RT

Citation Information


NTP. 7,12-Dimethylbenzanthracene (57-97-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
Valencia, R., Mason, J.M., and Zimmering, S. Chemical mutagenesis testing in Drosophila. IV. Interlaboratory comparison of mutagenicity tests after treatment of larvae. Environ. Molec. Mutagen. Vol. 14 (1989) 238-244

Study Data


Toxicity and Carcinogenicity Studies


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Initiation/Promotion Evaluation of the Toxicity (C60902B) of 1,2-Dihydro-2,2,4-trimethylquinoline (Monomer) (147-47-7) in Sencar Mice Exposed via Topical Application
Initiation/Promotion Evaluation of the Toxicity (C61994C) of Init/Prom Comparative Mouse Study (DMBA/TPA/BPO/MNNG) (INIT/PROM) in Sencar Mice Exposed via Topical Application