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2,4-Toluene diisocyanate (584-84-9)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7026156

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 2,4-Toluene diisocyanate (584-84-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2,4-Toluene diisocyanate (584-84-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,4-Toluene diisocyanate (584-84-9).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. 2,4-Toluene diisocyanate (584-84-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2,4-Toluene Diisocyanate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 928398
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0208) of 2,4-Toluene diisocyanate (584-84-9) in F344 Rats Exposed via Gavage Administration
Data Summary

DTT Data Collections