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Polybrominated biphenyl (67774-32-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0021173

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Polybrominated biphenyl (67774-32-7).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Polybrominated biphenyl (67774-32-7).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Polybrominated biphenyl (67774-32-7).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Polybrominated biphenyl (67774-32-7).
Drosophila Germ Cell Mutagenicity
SLRL

Citation Information

NTP. Polybrominated biphenyl (67774-32-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-398 Toxicology and Carcinogenesis Studies of Polybrominated Biphenyls (Firemaster FF-1") (CASRN 67774-32-7) in F344/N Rats and B6C3F1 Mice (Feed Studies)
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C53634B) of Polybrominated Biphenyl Mixture (Firemaster FF-1) (67774-32-7) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C53634B) of Polybrominated Biphenyl Mixture (Firemaster FF-1) (67774-32-7) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Polybrominated Biphenyl Mixture (Firemaster FF-1) (67774-32-7) in Micronucleus Study 338141 in B6C3F1 Mice
Summary and Individual Animal Data

NTP Data Collections