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Cytarabine hydrochloride (69-74-9)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5024891

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Cytarabine hydrochloride (69-74-9).
Micronucleus - Mice
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  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Cytarabine hydrochloride (69-74-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Cytarabine hydrochloride (69-74-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Cytarabine hydrochloride (69-74-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Equivocal

Citation Information

NTP. Cytarabine hydrochloride (69-74-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Cytarabine Hydrochloride (69-74-9) in Micronucleus Study 695078 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cytarabine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 163312
Summary Data
Genetic Toxicity Evaluation of Cytarabine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 170468
Summary Data

DTT Data Collections