1,1,1-Trichloroethane (71-55-6)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0021381
Study Results
Chronic Bioassay Level of Evidence
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Mice | |
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Genetic Toxicology
Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C04626C) of 1,1,1-Trichloroethane (71-55-6) in F344 Rats Exposed via Microcapsules in Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C04626C) of 1,1,1-Trichloroethane (71-55-6) in B6C3F1 Mice Exposed via Microcapsules in Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C04626) of 1,1,1-Trichloroethane (71-55-6) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C04626C) of 1,1,1-Trichloroethane (71-55-6) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C04626C) of 1,1,1-Trichloroethane (71-55-6) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,1-Trichloroethane (71-55-6) in Male Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,1-Trichloroethane (71-55-6) in Female Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,1-Trichloroethane (71-55-6) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,1-Trichloroethane (71-55-6) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Cytogenetic Study of 1,1,1-Trichloroethane in Chinese Hamster Ovary Cell Chromosome Aberrations Test
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane (71-55-6) in Micronucleus Study A09633 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane (71-55-6) in Micronucleus Study B09633 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 098436
Summary Data
- G06 - Ames Summary Data (142 KB)
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 677121
Summary Data
- G06 - Ames Summary Data (129 KB)
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 797607
Summary Data
- G06 - Ames Summary Data (130 KB)
Genetic Toxicity Evaluation of 1,1,1-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 844035
Summary Data
- G06 - Ames Summary Data (130 KB)
Other NTP Studies
ADME/TK Evaluation (S0091) of 1,1,1-Trichloroethane (71-55-6) in F344 Rats and B6C3F1 Mice Exposed via Gavage Administration and Intravenous Injection
Prenatal Developmental Toxicity Study (T0179) of 1,1,1-Trichloroethane (71-55-6) in Sprague-Dawley Rats Exposed via Dosed Water
Individual and Summary Data
- Dam Data: Dam Body Weights (15 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Organ Weights (25 kB)
- Fetal Data: All Malformations (696 kB)
- Fetal Data: All Variations (696 kB)
- Fetal Data: Fetal Body Weights (691 kB)
- Live Litter: All Litter (693 kB)
- Live Litter: Live Litter (697 kB)