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p,p'-Dichlorodiphenyl dichloroethylene (72-55-9)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to p,p'-Dichlorodiphenyl dichloroethylene (72-55-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to p,p'-Dichlorodiphenyl dichloroethylene (72-55-9).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to p,p'-Dichlorodiphenyl dichloroethylene (72-55-9).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to p,p'-Dichlorodiphenyl dichloroethylene (72-55-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. p,p'-Dichlorodiphenyl dichloroethylene (72-55-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-131 Bioassays of DDT, TDE, and p,p'-DDE for Possible Carcinogenicity (CASRN 50-29-3, CASRN 72-54-8, CASRN 72-55-9)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
In utero Exposure to DDT and Incidence of Diarrhea Among Boys from Tropical Mexico Lea A. Cupul-Uicab, Efraín A. Terrazas-Medina, Mauricio Hernández-Ávila, Matthew P. Longnecker.
Environmental Research (2017). DOI: https://doi.org/10.1016/j.envres.2017.08.027 PMID: 28841520

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of p,p'-Dichlorodiphenyl Dichloroethylene (72-55-9) in Male Osborne-Mendel Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of p,p'-Dichlorodiphenyl Dichloroethylene (72-55-9) in Female Osborne-Mendel Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of p,p'-Dichlorodiphenyl Dichloroethylene (72-55-9) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of p,p'-Dichlorodiphenyl Dichloroethylene (72-55-9) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of p,p'-Dichlorodiphenyl Dichloroethylene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 161546
Summary Data
Genetic Toxicity Evaluation of p,p'-Dichlorodiphenyl Dichloroethylene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 797103
Summary Data

NTP Data Collections