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Heptachlor (76-44-8)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020679

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Equivocal, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Heptachlor (76-44-8).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Heptachlor (76-44-8).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Not a Valid Test
  • View
    • Weakly Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Heptachlor (76-44-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. Heptachlor (76-44-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-009 Bioassay of Heptachlor for Possible Carcinogenicity (CASRN 76-44-8)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Heptachlor (76-44-8) in Male Osborne-Mendel Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Heptachlor (76-44-8) in Female Osborne-Mendel Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Heptachlor (76-44-8) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Heptachlor (76-44-8) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Heptachlor in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 339937
Summary Data
Genetic Toxicity Evaluation of Heptachlor in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 939541
Summary Data

Other NTP Studies

Screen for Developmental Toxicity in Zebrafish- Study 1
Results

NTP Data Collections