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Isobutyraldehyde (78-84-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9021635


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Isobutyraldehyde (78-84-2).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Isobutyraldehyde (78-84-2).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Isobutyraldehyde (78-84-2).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Isobutyraldehyde (78-84-2).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Isobutyraldehyde (78-84-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Isobutyraldehyde (78-84-2).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Isobutyraldehyde (78-84-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Equivocal

Citation Information


NTP. Isobutyraldehyde (78-84-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-472 Toxicology and Carcinogenesis Studies of Isobutyraldehyde (CASRN 78-84-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60968B) of Isobutyraldehyde (78-84-2) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C60968B) of Isobutyraldehyde (78-84-2) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Isobutyraldehyde (78-84-2) in Micronucleus Study A56966 in F344 Rats
Genetic Toxicity Evaluation of Isobutyraldehyde (78-84-2) in Micronucleus Study A60444 in B6C3F1 Mice
Genetic Toxicity Evaluation of Isobutyraldehyde (78-84-2) in Micronucleus Study A73413 in B6C3F1 Mice
Genetic Toxicity Evaluation of Isobutyraldehyde in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 700142
Summary Data
Genetic Toxicity Evaluation of Isobutyraldehyde in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 941876
Summary Data