U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

1,1,2-Trichloroethane (79-00-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5021380

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 1,1,2-Trichloroethane (79-00-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 1,1,2-Trichloroethane (79-00-5).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1,1,2-Trichloroethane (79-00-5).
Bacterial Mutagenicity
View
  • Negative
View
  • Equivocal
View
  • Negative
View
  • Negative

Citation Information

NTP. 1,1,2-Trichloroethane (79-00-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-074 Bioassay of 1,1,2-Trichloroethane for Possible Carcinogenicity (CASRN 79-00-5)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,2-Trichloroethane (79-00-5) in Male Osborne-Mendel Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,2-Trichloroethane (79-00-5) in Female Osborne-Mendel Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,2-Trichloroethane (79-00-5) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,1,2-Trichloroethane (79-00-5) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 1,1,2-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 590584
Summary Data
Genetic Toxicity Evaluation of 1,1,2-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 624635
Summary Data
Genetic Toxicity Evaluation of 1,1,2-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 946672
Summary Data
Genetic Toxicity Evaluation of 1,1,2-Trichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A38940
Summary Data

NTP Data Collections