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Methyl methacrylate (80-62-6)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Methyl methacrylate (80-62-6).
Micronucleus - Mice
View
  • Male: Equivocal
View
  • Male: Equivocal
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Methyl methacrylate (80-62-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Methyl methacrylate (80-62-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Methyl methacrylate (80-62-6).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Methyl methacrylate (80-62-6).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Negative
View
  • Negative

Citation Information


NTP. Methyl methacrylate (80-62-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-314 Toxicology and Carcinogenesis Studies of Methyl Methacrylate (CASRN 80-62-6) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Methyl Methacrylate (80-62-6) in Male F344 Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Methyl Methacrylate (80-62-6) in Female F344 Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Methyl Methacrylate (80-62-6) in Male B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Methyl Methacrylate (80-62-6) in Female B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Methyl Methacrylate (80-62-6) in Micronucleus Study 011066 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Methyl Methacrylate (80-62-6) in Micronucleus Study 211002 in B6C3F1 Mice
Genetic Toxicity Evaluation of Methyl Methacrylate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 284726
Summary Data
Genetic Toxicity Evaluation of Methyl Methacrylate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 683759
Summary Data
Genetic Toxicity Evaluation of Methyl Methacrylate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 689062
Summary Data