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1-Amino-2,4-dibromoanthraquinone (81-49-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4039235


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 1-Amino-2,4-dibromoanthraquinone (81-49-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1-Amino-2,4-dibromoanthraquinone (81-49-2).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. 1-Amino-2,4-dibromoanthraquinone (81-49-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-383 Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CASRN 81-49-2) in F344 Rats and B6C3F1 Mice (Feed Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C55458) of 1-Amino-2,4-dibromoanthraquinone (81-49-2) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C55458) of 1-Amino-2,4-dibromoanthraquinone (81-49-2) in B6C3F1 Mice Exposed via Dosed Feed

Other NTP Studies


ADME/TK Evaluation (S0212) of 1-Amino-2,4-dibromoanthraquinone (81-49-2) in F344 Rats Exposed via Gavage Administration or Intravenous Injection