U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Diethylphthalate (84-66-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7021780

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • Equivocal Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Diethylphthalate (84-66-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diethylphthalate (84-66-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. Diethylphthalate (84-66-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-429 Toxicology and Carcinogenesis Studies of Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1 Mice (Dermal Studies) with Dermal Initiation/Promotion Study of Diethylphthalate and Dimethylphthalate (CASRN 131-11-3) in Male Swiss (CD-1®) Mice
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Developmental Toxicity Evaluation of Diethyl Phthalate Administered to CD Rats on Gestational Days 6 through 15

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C60048B) of Diethyl Phthalate (84-66-2) in F344/N Rats Exposed via Topical Application
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C60048B) of Diethyl Phthalate (84-66-2) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Diethyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 364986
Summary Data
Genetic Toxicity Evaluation of Diethyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 576172
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0044) of Diethyl phthalate (84-66-2) in F344 Rats Exposed via Dermal Application
Data Summary
Prenatal Developmental Toxicity Study (TER88065) of Diethyl Phthalate (84-66-2) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data

NTP Data Collections