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Dibutyl phthalate (84-74-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2021781


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Dibutyl phthalate (84-74-2).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Dibutyl phthalate (84-74-2).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dibutyl phthalate (84-74-2).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Dibutyl phthalate (84-74-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-600 Toxicology and Carcinogenesis Studies of Di-n-butyl Phthalate Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley SD) Rats and B6C3F1/N Mice
TOX-30 Toxicity Studies of Dibutyl Phthalate (CASRN 84-74-2) Administered in Feed to F344/N Rats and B6C3F1Mice
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027A) of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Syrian Golden Hamsters Exposed via Dosed Feed
Evaluation of the Chronic (with Perinatal Exposure) Toxicity and Carcinogenicity (C10987) of Dibutyl Phthalate (84-74-2) in Harlan Sprague Dawley Rats Exposed via Dosed Feed
Chronic (with Perinatal Exposure) Study Tables
Chronic (with Perinatal Exposure) Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C10987) of Dibutyl Phthalate (84-74-2 ) in B6C3F1/N, Mouse Exposed Via Dosed Feed
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Peroxisome Project (Dibutyl Phthalate) (84-74-2) in Micronucleus Study A17278 in B6C3F1 Mice
Genetic Toxicity Evaluation of Peroxisome Project (Dibutyl Phthalate) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 077089
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0045) of Dibutyl phthalate (84-74-2) in F344 Rats Exposed via Dermal Application
Toxicokinetic Evaluation (S0545) of Di-n-Butyl Phthalate (84-74-2) in Sprague-Dawley Rats, Syrian Golden Hamsters, and B6C3F1 Mice Exposed via Dosed Feed, Intravenous Injection or Gavage
Toxicokinetic Evaluation (S0580) of Di-n-Butyl Phthalate (84-74-2) in Sprague-Dawley Rats, Syrian Golden Hamsters, and B6C3F1 Mice Exposed via Dosed Feed
Data