Ginkgo biloba extract (90045-36-6)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8031366
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
| Micronucleus - Rats |
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| Micronucleus - Mice |
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| Bacterial Mutagenicity |
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Publications
TR-578
Toxicology and Carcinogenesis Studies of Ginkgo Biloba Extract (CASRN 90045-36-6) in F344/N Rats and B6C3F1/N Mice (Gavage Studies)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (66 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 kB)
- P04 - Neoplasms by Individual Animal (649 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 kB)
- P08 - Statistical Analysis of Primary Tumors (229 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (828 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (450 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (579 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (57 kB)
- P40 - Survival Curves (65 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (377 kB)
- Female Individual Animal Clinical Observations (225 kB)
- Female Individual Animal Neoplastic Pathology Data (158 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (351 kB)
- Male Individual Animal Clinical Observations (196 kB)
- Male Individual Animal Neoplastic Pathology Data (234 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (69 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (58 kB)
- P04 - Neoplasms by Individual Animal (680 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 kB)
- P08 - Statistical Analysis of Primary Tumors (180 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (873 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (573 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (597 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (60 kB)
- P40 - Survival Curves (65 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (323 kB)
- Female Individual Animal Clinical Observations (40 kB)
- Female Individual Animal Neoplastic Pathology Data (184 kB)
- Female Individual Animal Non Neoplastic Pathology Data (901 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (391 kB)
- Male Individual Animal Clinical Observations (85 kB)
- Male Individual Animal Neoplastic Pathology Data (202 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Special Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050 in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050B in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050C in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050D in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050E in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba Extract (90045-36-6) in Micronucleus Study A97646 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A33386
Summary Data
- G06 - Ames Summary Data (68 KB)
Other NTP Studies
Toxicokinetic Evaluation (K99050) of Ginkgo biloba (DTXSID8031366) in Rat
Data
- Annotated Group Parameters (16 kB)
- Summary Data - Ginkgo Biloba Extract, Bilobalide (218 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide A (219 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide B (216 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide C (223 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide J (217 kB)
- Summary Data - Ginkgo Biloba Extract, Isorhamnetin (218 kB)
- Summary Data - Ginkgo Biloba Extract, Kaempferol (218 kB)
- Summary Data - Ginkgo Biloba Extract, Quercetin (176 kB)