Botanicals
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
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Micronucleus - Rats |
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Mammalian Cell Cytogenetics | |
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Bacterial Mutagenicity |
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Publications
TR-603
Toxicity Studies of Black Cohosh Administered via Oral Gavage to Harlan Sprague-Dawley Rats and B6C3F1/N Mice
Study Data
Toxicity and Carcinogenicity Studies
22-Day Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in F344/N Tac Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
28-Day Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (369 kB)
- E04 - Mean Body Weights and Survival Table (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (21 kB)
- P04 - Neoplasms by Individual Animal (146 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (22 kB)
- P08 - Statistical Analysis of Primary Tumors (7 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (138 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (59 kB)
- P14 - Individual Animal Pathology Data (163 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (21 kB)
- P40 - Survival Curves (395 kB)
- PA06 - Organ Weights Summary (153 kB)
- PA41 - Clinical Chemistry Summary (508 kB)
- PA43 - Hematology Summary (582 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R07 - Hormone Summary (102 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (12 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Clinical Chemistry Data (24 kB)
- Individual Animal Cytochrome Activity Data (14 kB)
- Individual Animal Hematology Data (32 kB)
- Individual Animal Hormone Data (14 kB)
- Individual Animal Organ Weight Data (20 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (10 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
28-Day Evaluation of the Prechronic Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT ) in B6C3F1 Mice Exposed Via Gavage
Study Tables
- E03 - Growth Curves (406 kB)
- E04 - Mean Body Weights and Survival Table (13 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 kB)
- P04 - Neoplasms by Individual Animal (138 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (23 kB)
- P08 - Statistical Analysis of Primary Tumors (8 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (74 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (24 kB)
- P14 - Individual Animal Pathology Data (155 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 kB)
- P40 - Survival Curves (390 kB)
- PA06 - Organ Weights Summary (152 kB)
- PA41 - Clinical Chemistry Summary (174 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (2 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Clinical Chemistry Data (17 kB)
- Individual Animal Cytochrome Activity Data (9 kB)
- Individual Animal Organ Weight Data (15 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (3 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
18-33 Day Evaluation of the Toxicity (C20101) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in F344 Rats Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
Clinical Chemistry Reports
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
26-39 Week Evaluation of the Toxicity (C20101B) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
3-Month Evaluation of the Toxicity (C20316) of Cedarwood Oil (8000-27-9) in F 344/N Rats Exposed via Topical Application
Study Tables
- E03 - Growth Curves (428 kB)
- E04 - Mean Body Weights and Survival Table (22 kB)
- E05 - Clinical Observations Summary (19 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (57 kB)
- P04 - Neoplasms by Individual Animal (264 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (55 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (303 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions Untreated and High Dose Only (224 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions without High Dose (206 kB)
- P14 - Individual Animal Pathology Data (362 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (59 kB)
- P40 - Survival Curves (438 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (40 kB)
- Female Individual Animal Clinical Observations (219 kB)
- Female Individual Animal Non Neoplastic Pathology Data (135 kB)
- Female Individual Animal Organ Weight Data (21 kB)
- Female Individual Animal Survival Data (13 kB)
- Male Individual Animal Body Weight Data (40 kB)
- Male Individual Animal Clinical Observations (208 kB)
- Male Individual Animal Non Neoplastic Pathology Data (196 kB)
- Male Individual Animal Organ Weight Data (21 kB)
- Male Individual Animal Survival Data (13 kB)
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in F344/NTac Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (85 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (15 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (25 kB)
- P04 - Neoplasms by Individual Animal (135 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (150 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (159 kB)
- P14 - Individual Animal Pathology Data (269 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (26 kB)
- P40 - Survival Curves (77 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Clinical Observations (8 kB)
- Female Individual Animal Non Neoplastic Pathology Data (103 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Non Neoplastic Pathology Data (113 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (455 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (231 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (237 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (191 kB)
- P14 - Individual Animal Pathology Data (265 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (435 kB)
- PA06 - Organ Weights Summary (153 kB)
- PA41 - Clinical Chemistry Summary (508 kB)
- PA43 - Hematology Summary (582 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R06 - Andrology Summary (51 kB)
- R07 - Hormone Summary (102 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (27 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Female Individual Clinical Observations (2 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Clinical Chemistry Data (24 kB)
- Individual Animal Hematology Data (32 kB)
- Individual Animal Hormone Data (14 kB)
- Individual Animal Organ Weight Data (20 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Non Neoplastic Pathology Data (27 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (2 kB)
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
3-Month Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (86 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (15 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (24 kB)
- P04 - Neoplasms by Individual Animal (139 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (154 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (144 kB)
- P14 - Individual Animal Pathology Data (273 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (26 kB)
- P40 - Survival Curves (78 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (34 kB)
- Female Individual Animal Clinical Observations (3 kB)
- Female Individual Animal Non Neoplastic Pathology Data (67 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (34 kB)
- Male Individual Animal Clinical Observations (2 kB)
- Male Individual Animal Neoplastic Pathology Data (2 kB)
- Male Individual Animal Non Neoplastic Pathology Data (79 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20316) of Cedarwood Oil (8000-27-9) in B6C3F1 Mice Exposed via Topical Application
Study Tables
- E03 - Growth Curves (432 kB)
- E04 - Mean Body Weights and Survival Table (22 kB)
- E05 - Clinical Observations Summary (19 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (56 kB)
- P04 - Neoplasms by Individual Animal (310 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (55 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (357 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions Untreated and High Dose Only (136 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions without High Dose (163 kB)
- P14 - Individual Animal Pathology Data (417 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (58 kB)
- P40 - Survival Curves (429 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (39 kB)
- Female Individual Animal Clinical Observations (250 kB)
- Female Individual Animal Non Neoplastic Pathology Data (183 kB)
- Female Individual Animal Organ Weight Data (21 kB)
- Female Individual Animal Survival Data (13 kB)
- Male Individual Animal Body Weight Data (39 kB)
- Male Individual Animal Clinical Observations (272 kB)
- Male Individual Animal Non Neoplastic Pathology Data (190 kB)
- Male Individual Animal Organ Weight Data (21 kB)
- Male Individual Animal Survival Data (13 kB)
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (419 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (28 kB)
- P04 - Neoplasms by Individual Animal (193 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (125 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (48 kB)
- P14 - Individual Animal Pathology Data (364 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (29 kB)
- P40 - Survival Curves (433 kB)
- PA06 - Organ Weights Summary (152 kB)
- PA41 - Clinical Chemistry Summary (174 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R06 - Andrology Summary (51 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (50 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (8 kB)
- Female Individual Animal Survival Data (16 kB)
- Female Individual Animal Terminal Body Weight Data (27 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Clinical Chemistry Data (17 kB)
- Individual Animal Organ Weight Data (15 kB)
- Male Individual Animal Body Weight Data (50 kB)
- Male Individual Animal Non Neoplastic Pathology Data (5 kB)
- Male Individual Animal Survival Data (16 kB)
- Male Individual Animal Terminal Body Weight Data (27 kB)
- Male Individual Clinical Observations (2 kB)
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/NCTR Rats Exposed via Dosed Water
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (69 kB)
- P04 - Neoplasms by Individual Animal (813 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (71 kB)
- P40 - Survival Curves (87 kB)
Individual Animal Data
- Female Individual Animal Neoplastic Pathology Data (218 kB)
- Female Individual Animal Non Neoplastic Pathology Data (972 kB)
- Female Individual Animal Organ Weight Data (54 kB)
- Female Individual Animal Survival Data (32 kB)
- Male Individual Animal Neoplastic Pathology Data (385 kB)
- Male Individual Animal Non Neoplastic Pathology Data (998 kB)
- Male Individual Animal Organ Weight Data (54 kB)
- Male Individual Animal Survival Data (32 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C62204) of Safflower Oil (8001-23-8) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (526 kB)
- E04 - Mean Body Weights and Survival Table (20 kB)
- E05 - Clinical Observations Summary (23 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (56 kB)
- P04 - Neoplasms by Individual Animal (690 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P08 - Statistical Analysis of Primary Tumors (222 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (836 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (456 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (611 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (58 kB)
- P40 - Survival Curves (525 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (371 kB)
- Female Individual Animal Clinical Observations (171 kB)
- Female Individual Animal Neoplastic Pathology Data (139 kB)
- Female Individual Animal Non Neoplastic Pathology Data (776 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (327 kB)
- Male Individual Animal Clinical Observations (123 kB)
- Male Individual Animal Neoplastic Pathology Data (189 kB)
- Male Individual Animal Non Neoplastic Pathology Data (875 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (33 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C60015) of Turmeric, Oleoresin (Curcumin) (8024-37-1) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (66 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 kB)
- P04 - Neoplasms by Individual Animal (649 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 kB)
- P08 - Statistical Analysis of Primary Tumors (229 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (828 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (450 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (579 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (57 kB)
- P40 - Survival Curves (65 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (377 kB)
- Female Individual Animal Clinical Observations (225 kB)
- Female Individual Animal Neoplastic Pathology Data (158 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (351 kB)
- Male Individual Animal Clinical Observations (196 kB)
- Male Individual Animal Neoplastic Pathology Data (234 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in HSD, Rat Exposed Via GAVAGE
Study Tables
- Adjusted Pup Body Weights (181 kB)
- E01 - Animal Removal Summary by Treatment Group (13 kB)
- E01 - Animal Removal Summary by Treatment Group - Female Pup (7 kB)
- E01 - Animal Removal Summary by Treatment Group - Male Pup (7 kB)
- E02 - Animals Removed from Experiment (156 kB)
- E02 - Animals Removed from Experiment - Female Pup (128 kB)
- E02 - Animals Removed from Experiment - Male Pup (130 kB)
- E03 - Growth Curves (486 kB)
- E03 - Growth Curves - Female Pup (28 kB)
- E03 - Growth Curves - Male Pup (28 kB)
- E03 - Growth Curves Litter Based (65 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E04 - Mean Body Weights and Survival Table - Female Pup (8 kB)
- E04 - Mean Body Weights and Survival Table - Male Pup (8 kB)
- E04 - Mean Body Weights and Survival Table Litter Based (18 kB)
- E05 - Clinical Observations Summary (22 kB)
- E12 - Animal History - Female Pup (1 mB)
- E12 - Animal History - Male Pup (1 mB)
- Gestational Body Weights (31 kB)
- Lactational Body Weights (163 kB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (55 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (70 kB)
- P04 - Neoplasms by Individual Animal (677 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (51 kB)
- P08 - Statistical Analysis of Primary Tumors Litter Based (227 kB)
- P08 - Statistical Analysis of Primary Tumors Step Section (120 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (957 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions Litter Based (564 kB)
- P11 - Statistical Analysis of Survival Data (29 kB)
- P11 - Statistical Analysis of Survival Data Litter Based (21 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (618 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (72 kB)
- P40 - Survival Curves (491 kB)
- P40 - Survival Curves - Female Pup (29 kB)
- P40 - Survival Curves - Male Pup (29 kB)
- PND 1 Litter Data (27 kB)
- PND 4 and 21 Litter Size and Survival (34 kB)
- R02 - Reproductive Performance Summary (38 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (392 kB)
- Female Individual Animal Body Weight Data All Animals - Female Pup (224 kB)
- Female Individual Animal Clinical Observations (204 kB)
- Female Individual Animal Neoplastic Pathology Data (124 kB)
- Female Individual Animal Non Neoplastic Pathology Data (758 kB)
- Female Individual Animal Survival Data (34 kB)
- Female Individual Animal Survival Data - Female Pup (121 kB)
- Female Individual Animal Terminal Body Weight Data (57 kB)
- Individual Animal Clinical Observations Data (9 kB)
- Individual Animal DamID and PupID Data (17 kB)
- Individual Animal Reproductive Performance Data (11 kB)
- Individual Pup Census and Litter Weight by Sex Data (24 kB)
- Male Individual Animal Body Weight Data All Animals (391 kB)
- Male Individual Animal Body Weight Data All Animals - Male Pup (237 kB)
- Male Individual Animal Clinical Observations (257 kB)
- Male Individual Animal Neoplastic Pathology Data (103 kB)
- Male Individual Animal Non Neoplastic Pathology Data (906 kB)
- Male Individual Animal Survival Data (33 kB)
- Male Individual Animal Survival Data - Male Pup (128 kB)
- Male Individual Animal Terminal Body Weight Data (57 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20203) of Green Tea Extract (GREENTEAEXTR) in Wistar Han Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (70 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (66 kB)
- P04 - Neoplasms by Individual Animal (629 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (51 kB)
- P08 - Statistical Analysis of Primary Tumors (239 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (617 kB)
- P11 - Statistical Analysis of Survival Data (26 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (607 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (68 kB)
- P40 - Survival Curves (68 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (500 kB)
- Female Individual Animal Clinical Observations (92 kB)
- Female Individual Animal Neoplastic Pathology Data (108 kB)
- Female Individual Animal Non Neoplastic Pathology Data (833 kB)
- Female Individual Animal Organ Weight Data (63 kB)
- Female Individual Animal Survival Data (37 kB)
- Male Individual Animal Body Weight Data (395 kB)
- Male Individual Animal Clinical Observations (66 kB)
- Male Individual Animal Neoplastic Pathology Data (66 kB)
- Male Individual Animal Non Neoplastic Pathology Data (965 kB)
- Male Individual Animal Organ Weight Data (63 kB)
- Male Individual Animal Survival Data (37 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1/NCTR Mice Exposed via Dosed Water
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (59 kB)
- P04 - Neoplasms by Individual Animal (771 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (858 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (60 kB)
- P40 - Survival Curves (84 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (621 kB)
- Female Individual Animal Neoplastic Pathology Data (215 kB)
- Female Individual Animal Non Neoplastic Pathology Data (740 kB)
- Female Individual Animal Organ Weight Data (55 kB)
- Female Individual Animal Survival Data (32 kB)
- Male Individual Animal Body Weight Data (633 kB)
- Male Individual Animal Neoplastic Pathology Data (124 kB)
- Male Individual Animal Non Neoplastic Pathology Data (573 kB)
- Male Individual Animal Organ Weight Data (55 kB)
- Male Individual Animal Survival Data (32 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in B6C3F1/N, Mouse Exposed Via GAVAGE
Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (591 kB)
- Female Individual Animal Clinical Observations (48 kB)
- Female Individual Animal Neoplastic Pathology Data (165 kB)
- Female Individual Animal Non Neoplastic Pathology Data (525 kB)
- Female Individual Animal Survival Data (58 kB)
- Female Individual Animal Terminal Body Weight Data (98 kB)
- Individual Animal Bone Marrow Smear Data (12 kB)
- Individual Animal Hematology Data (17 kB)
Hematology and Bone Marrow and Spleen Organ Weight (3 and 12 Month)
- Abnormal Metarubicytes in Bone Marrow (27 kB)
- PA06 – Organ Weights Summary (45 kB)
- PA43 – Hematology Summary (275 kB)
- PA50 – Bone Marrow Smear Summary (165 kB)
Chronic Study Tables
- E01 - Animal Removal Summary by Treatment Group (9 kB)
- E02 - Animals Removed from Experiment (58 kB)
- E03 - Growth Curves (251 kB)
- E04 - Mean Body Weights and Survival Table (14 kB)
- E05 - Clinical Observations Summary (17 kB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (27 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (30 kB)
- P04 - Neoplasms by Individual Animal (418 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (22 kB)
- P08 - Statistical Analysis of Primary Tumors (54 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (470 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (135 kB)
- P11 - Statistical Analysis of Survival Data (14 kB)
- P14 - Individual Animal Pathology Data (572 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (330 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (31 kB)
- P40 - Survival Curves (237 kB)
3-Month Interim Study Tables
- E01 - Animal Removal Summary by Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (34 kB)
- E03 - Growth Curves (217 kB)
- E04 - Mean Body Weights and Survival Table (10 kB)
- E05 - Clinical Observations Summary (17 kB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (13 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (12 kB)
- P04 - Neoplasms by Individual Animal (59 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (14 kB)
- P06 - Organ Weight Summary (12 kB)
- P08 - Statistical Analysis of Primary Tumors (8 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (56 kB)
- P11 - Statistical Analysis of Survival Data (13 kB)
- P12 - Organ Weights by Individual Animal (103 kB)
- P13 - Organ Weights by Treatment Group (20 kB)
- P14 - Individual Animal Pathology Data (69 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (59 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (13 kB)
- P40 - Survival Curves (227 kB)
12-Month Study Tables
- E01 - Animal Removal Summary by Treatment Group (8 kB)
- E02 - Animals Removed from Experiment (25 kB)
- E03 - Growth Curves (218 kB)
- E04 - Mean Body Weights and Survival Table (11 kB)
- E05 - Clinical Observations Summary (17 kB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (12 kB)
- P04 - Neoplasms by Individual Animal (59 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (14 kB)
- P06 - Organ Weight Summary (12 kB)
- P08 - Statistical Analysis of Primary Tumors (9 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (58 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (14 kB)
- P11 - Statistical Analysis of Survival Data (13 kB)
- P12 - Organ Weights by Individual Animal (103 kB)
- P13 - Organ Weights by Treatment Group (20 kB)
- P14 - Individual Animal Pathology Data (71 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (59 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (13 kB)
- P40 - Survival Curves (225 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (538 kB)
- E04 - Mean Body Weights and Survival Table (20 kB)
- E05 - Clinical Observations Summary (22 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (50 kB)
- P04 - Neoplasms by Individual Animal (411 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (45 kB)
- P08 - Statistical Analysis of Primary Tumors (204 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (472 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (441 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (393 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (54 kB)
- P40 - Survival Curves (524 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (345 kB)
- Female Individual Animal Clinical Observations (40 kB)
- Female Individual Animal Neoplastic Pathology Data (104 kB)
- Female Individual Animal Non Neoplastic Pathology Data (753 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (391 kB)
- Male Individual Animal Clinical Observations (48 kB)
- Male Individual Animal Neoplastic Pathology Data (152 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C20203) of Green Tea Extract (GREENTEAEXTR) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (69 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 kB)
- P04 - Neoplasms by Individual Animal (621 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 kB)
- P08 - Statistical Analysis of Primary Tumors (219 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (782 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (465 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (571 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 kB)
- P40 - Survival Curves (63 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (354 kB)
- Female Individual Animal Clinical Observations (27 kB)
- Female Individual Animal Neoplastic Pathology Data (87 kB)
- Female Individual Animal Non Neoplastic Pathology Data (779 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (345 kB)
- Male Individual Animal Clinical Observations (64 kB)
- Male Individual Animal Neoplastic Pathology Data (116 kB)
- Male Individual Animal Non Neoplastic Pathology Data (897 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C60015) of Turmeric, Oleoresin (Curcumin) (8024-37-1) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (69 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (58 kB)
- P04 - Neoplasms by Individual Animal (680 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 kB)
- P08 - Statistical Analysis of Primary Tumors (180 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (873 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (573 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (597 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (60 kB)
- P40 - Survival Curves (65 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (323 kB)
- Female Individual Animal Clinical Observations (40 kB)
- Female Individual Animal Neoplastic Pathology Data (184 kB)
- Female Individual Animal Non Neoplastic Pathology Data (901 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (391 kB)
- Male Individual Animal Clinical Observations (85 kB)
- Male Individual Animal Neoplastic Pathology Data (202 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
Special Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
Pathology Tables
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Actaea racemosa (Black Cohosh) XRM in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058V
Summary Data
- G06 - Ames Summary Data (68 KB)
Genetic Toxicity Evaluation of Aloe Vera Charcoal Filtered Whole Leaf Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03042
Summary Data
- G06 - Ames Summary Data (93 KB)
Genetic Toxicity Evaluation of Aloe Vera Gel in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A20251
Summary Data
- G06 - Ames Summary Data (145 KB)
Genetic Toxicity Evaluation of Aloe Vera Gel in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99056
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Aloe Vera Whole Leaf Extract (Native) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03041
Summary Data
- G06 - Ames Summary Data (92 KB)
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44526
Summary Data
- G06 - Ames Summary Data (279 KB)
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A50684
Summary Data
- G06 - Ames Summary Data (159 KB)
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A82879
Summary Data
- G06 - Ames Summary Data (159 KB)
Genetic Toxicity Evaluation of Bixin (6983-79-5) in Micronucleus Study F68597 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Bixin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A24885
Summary Data
- G06 - Ames Summary Data (77 KB)
Genetic Toxicity Evaluation of Bixin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42709
Summary Data
- G06 - Ames Summary Data (78 KB)
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058 in Wistar Han Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058B in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058C in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058E in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (BCE_3012781) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Y
Summary Data
- G06 - Ames Summary Data (68 KB)
Genetic Toxicity Evaluation of Black Cohosh (BCE_BCO2.5-A2401090310) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058X
Summary Data
- G06 - Ames Summary Data (63 KB)
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE2) (BCE_TP20141210-R) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Z
Summary Data
- G06 - Ames Summary Data (63 KB)
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A13815
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058D
Genetic Toxicity Evaluation of Cedarwood Oil (8000-27-9) in Micronucleus Study A16009 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cedarwood Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A51043
Summary Data
- G06 - Ames Summary Data (59 KB)
Genetic Toxicity Evaluation of Curcumin (458-37-7) in Micronucleus Study A43540 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Curcumin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 489345
Summary Data
- G06 - Ames Summary Data (264 KB)
Genetic Toxicity Evaluation of Curcumin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A73195
Summary Data
- G06 - Ames Summary Data (145 KB)
Genetic Toxicity Evaluation of Dong Quai in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A72844
Summary Data
- G06 - Ames Summary Data (68 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067
Summary Data
- G06 - Ames Summary Data (74 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067BIR
Summary Data
- G06 - Ames Summary Data (38 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067C
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067CIR
Summary Data
- G06 - Ames Summary Data (62 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067E
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067EIR
Summary Data
- G06 - Ames Summary Data (91 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067FIR
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067GIR
Summary Data
- G06 - Ames Summary Data (81 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067H
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067HIR
Summary Data
- G06 - Ames Summary Data (57 KB)
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067IR
Summary Data
- G06 - Ames Summary Data (57 KB)
Genetic Toxicity Evaluation of Garcinia Cambogia Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G05016
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G03008 in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050 in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050B in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050C in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050D in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050E in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba Extract (90045-36-6) in Micronucleus Study A97646 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginkgo Biloba Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A33386
Summary Data
- G06 - Ames Summary Data (68 KB)
Genetic Toxicity Evaluation of Ginseng (50647-08-0) in Micronucleus Study A82446 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ginseng in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A04849
Summary Data
- G06 - Ames Summary Data (79 KB)
Genetic Toxicity Evaluation of Ginseng in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A16457
Summary Data
- G06 - Ames Summary Data (213 KB)
Genetic Toxicity Evaluation of Goldenseal Root Powder (GOLDENSEALRT) in Micronucleus Study A21831 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Goldenseal Root Powder in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A83314
Summary Data
- G06 - Ames Summary Data (67 KB)
Genetic Toxicity Evaluation of Grape Seed Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A03106
Summary Data
- G06 - Ames Summary Data (154 KB)
Genetic Toxicity Evaluation of Green Tea Extract (GREENTEAEXTR) in Micronucleus Study A70207 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Green Tea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A43286
Summary Data
- G06 - Ames Summary Data (82 KB)
Genetic Toxicity Evaluation of Gum Guggul Extract (GUMGUGGULEXT) in Micronucleus Study G05066 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Gum Guggul Extract (GUMGUGGULEXT) in Micronucleus Study G05066B in B6C3F1 Mice
Genetic Toxicity Evaluation of Juglone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A50290
Summary Data
- G06 - Ames Summary Data (260 KB)
Genetic Toxicity Evaluation of Kava Kava Extract (9000-38-8) in Micronucleus Study A53705 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A00186
Summary Data
- G06 - Ames Summary Data (157 KB)
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A88186
Summary Data
- G06 - Ames Summary Data (74 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract (84604-20-6) in Micronucleus Study A73501 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A21904
Summary Data
- G06 - Ames Summary Data (70 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41673
Summary Data
- G06 - Ames Summary Data (199 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42260
Summary Data
- G06 - Ames Summary Data (72 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44499
Summary Data
- G06 - Ames Summary Data (140 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A78884
Summary Data
- G06 - Ames Summary Data (71 KB)
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99059
Summary Data
- G06 - Ames Summary Data (91 KB)
Genetic Toxicity Evaluation of Norbixin (cis/trans Mixture) (542-40-5) in Micronucleus Study F34414 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Norbixin (cis/trans Mixture) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A63936
Summary Data
- G06 - Ames Summary Data (85 KB)
Genetic Toxicity Evaluation of Pine Bark Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A91384
Genetic Toxicity Evaluation of Safflower Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 469522
Summary Data
- G06 - Ames Summary Data (133 KB)
Genetic Toxicity Evaluation of Senna (Powdered) (8013-11-4) in Micronucleus Study GEMT28 in P53 +/- (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 840294
Summary Data
- G06 - Ames Summary Data (112 KB)
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A09328
Summary Data
- G06 - Ames Summary Data (158 KB)
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A10901
Summary Data
- G06 - Ames Summary Data (79 KB)
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study GEMT28B
Summary Data
- G06 - Ames Summary Data (79 KB)
Genetic Toxicity Evaluation of Sennoside A in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G01053
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Turmeric, Oleoresin (Curcumin) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 857432
Summary Data
- G06 - Ames Summary Data (134 KB)
Genetic Toxicity Evaluation of Valerian (Valeriana officinalis L.) Root Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A66100
Summary Data
- G06 - Ames Summary Data (125 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345B
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345C
Summary Data
- G06 - Ames Summary Data (77 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345D
Summary Data
- G06 - Ames Summary Data (76 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345E
Summary Data
- G06 - Ames Summary Data (79 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345F
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345G
Summary Data
- G06 - Ames Summary Data (77 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345H
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345I
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345J
Summary Data
- G06 - Ames Summary Data (74 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345K
Summary Data
- G06 - Ames Summary Data (73 KB)
Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345L
Summary Data
- G06 - Ames Summary Data (74 KB)
Genetic Toxicity Evaluation of Valerian Root Extract (8057-49-6) in Micronucleus Study G09042 in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE3) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058W
Summary Data
- G06 - Ames Summary Data (85 KB)
Other NTP Studies
Prenatal Developmental Toxicity Pilot Study (TRP98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (20 kB)
- Dam Data: Dam Feed Consumption (18 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (18 kB)
- Dam Data: Organ Weights (20 kB)
- Fetal Data: All Malformations (456 kB)
- Fetal Data: All Variations (456 kB)
- Fetal Data: Fetal Body Weights (452 kB)
- Live Litter: All Litter (455 kB)
- Live Litter: Live Litter (456 kB)
Prenatal Developmental Toxicity Pilot Study (TRP99007) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (18 kB)
- Dam Data: Dam Feed Consumption (17 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (17 kB)
- Dam Data: Organ Weights (20 kB)
- Fetal Data: All Malformations (403 kB)
- Fetal Data: Fetal Body Weights (399 kB)
- Live Litter: All Litter (402 kB)
- Live Litter: Live Litter (403 kB)
Prenatal Developmental Toxicity Study (TER98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (26 kB)
- Dam Data: Dam Feed Consumption (24 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (24 kB)
- Dam Data: Organ Weights (26 kB)
- Fetal Data: All Malformations (694 kB)
- Fetal Data: All Variations (693 kB)
- Fetal Data: Fetal Body Weights (689 kB)
- Live Litter: All Litter (691 kB)
- Live Litter: Live Litter (694 kB)
Prenatal Developmental Toxicity Study (TER99004) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (20 kB)
- Dam Data: Dam Feed Consumption (18 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (18 kB)
- Dam Data: Organ Weights (21 kB)
- Fetal Data: All Malformations (522 kB)
- Fetal Data: All Variations (522 kB)
- Fetal Data: Fetal Body Weights (518 kB)
- Live Litter: All Litter (520 kB)
- Live Litter: Live Litter (523 kB)
Toxicokinetic Evaluation (K99050) of Ginkgo biloba (DTXSID8031366) in Rat
Data
- Annotated Group Parameters (16 kB)
- Summary Data - Ginkgo Biloba Extract, Bilobalide (218 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide A (219 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide B (216 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide C (223 kB)
- Summary Data - Ginkgo Biloba Extract, Ginkgolide J (217 kB)
- Summary Data - Ginkgo Biloba Extract, Isorhamnetin (218 kB)
- Summary Data - Ginkgo Biloba Extract, Kaempferol (218 kB)
- Summary Data - Ginkgo Biloba Extract, Quercetin (176 kB)
Other Studies
4-Week Immunotoxicity Evaluation (IMM20701) of Gum Guggul 2.5% granules (GUMGUGGULEXT) in Female B6C3F1 Mice Exposed via Gavage
Statistical Tables
- Body weight and body weight gain in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (22 kB)
- Cell mediated Immunity in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (part 1) (24 kB)
- Cell mediated Immunity in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (part 2) (24 kB)
- Functional activity of the mononuclear phagocytic system in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (27 kB)
- Hematology and blood leukocyte differentials in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (110 kB)
- Humoral mediated Immunity in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (103 kB)
- Natural killer cell activity in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (22 kB)
- Organ weights in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (56 kB)
- Spleen cell immunophenotyping in female B6C3F1N mice exposed to gum guggul extract via oral gavage daily for 28 days (39 kB)
Individual Animal Data
- 002-03228-0005-0000-2 Female IndividualAnimalSurvival (11 kB)
- 002-03228-0005-0000-2 Female IndividualBodyWeight (12 kB)
- 002-03228-0005-0000-2 Female NonNeoplastic (19 kB)
- 002-03228-0005-0000-2 OrganWeights Female OrganWeightsIndividualAnimal (18 kB)
- Individual Animal ANTI-CD3 Proliferation Data (20 kB)
- Individual Animal Body Weight Data (106 kB)
- Individual Animal Gross Observations Data (61 kB)
- Individual Animal Hematology Data (22 kB)
- Individual Animal Histo Pathology Data (9 kB)
- Individual Animal In Vitro Cytotoxic T Lymphocyte Data (30 kB)
- Individual Animal Leukocyte Cell Differential Data (9 kB)
- Individual Animal Mixed Leukocyte Response Data (23 kB)
- Individual Animal Mononuclear Phagocytic System Data (36 kB)
- Individual Animal Natural Killer Cell Activity Data (23 kB)
- Individual Animal Organ Weight Data (36 kB)
- Individual Animal Periodic Weight Gain Data (93 kB)
- Individual Animal Reticulocytes Data (7 kB)
- Individual Animal Serum Anti-KLH ELISA Data (7 kB)
- Individual Animal Serum IgM Data (18 kB)
- Individual Animal Surface Markers Absolute Data (22 kB)
- Individual Animal Surface Markers Percentage Data (22 kB)
- Individual Animal T-Dependent Antibody Response Data (21 kB)