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Botanicals


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
View
  • Some Evidence, Female, Rats
  • Some Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice
View
  • Equivocal Evidence, Female, Mice
  • Equivocal Evidence, Male, Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice
  • Some Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Botanicals.
Micronucleus - Mice
View
  • Male: Negative
    Female: Weakly Positive
View
  • Male: Negative
    Female: Negative
View
  • Female: Positive
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Equivocal
View
  • Male: Negative
View
  • Male: Negative
View
  • Female: Positive
View
  • Female: Positive
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Botanicals.
Micronucleus - Rats
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
View
  • Male: Negative
View
  • Male: Negative
View
  • Male: Negative
View
  • Male: Negative
View
  • Female: Positive
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Botanicals.
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
  • View
    • Weakly Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Botanicals.
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Equivocal
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Negative
View
  • Equivocal
View
  • Negative
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Negative
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Equivocal
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Positive

Citation Information


NTP. Botanicals. Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-603 Toxicity Studies of Black Cohosh Administered via Oral Gavage to Harlan Sprague-Dawley Rats and B6C3F1/N Mice

Study Data


Toxicity and Carcinogenicity Studies


22-Day Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in F344/N Tac Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
28-Day Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
28-Day Evaluation of the Prechronic Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT ) in B6C3F1 Mice Exposed Via Gavage
18-33 Day Evaluation of the Toxicity (C20101) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
2-Week Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
26-39 Week Evaluation of the Toxicity (C20101B) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C20316) of Cedarwood Oil (8000-27-9) in F 344/N Rats Exposed via Topical Application
Study Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in F344/NTac Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1 Mice Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C20203) of Green Tea Extract (GREENTEAEXTR) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C20316) of Cedarwood Oil (8000-27-9) in B6C3F1 Mice Exposed via Topical Application
Study Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/NCTR Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C62204) of Safflower Oil (8001-23-8) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20005) of Ginseng (50647-08-0) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C60015) of Turmeric, Oleoresin (Curcumin) (8024-37-1) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in HSD, Rat Exposed Via GAVAGE
Study Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C20203) of Green Tea Extract (GREENTEAEXTR) in Wistar Han Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1/NCTR Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in B6C3F1/N, Mouse Exposed Via GAVAGE
Individual Animal Data
Hematology and Bone Marrow and Spleen Organ Weight (3 and 12 Month)
Chronic Study Tables
3-Month Interim Study Tables
12-Month Study Tables
Evaluation of the Chronic Toxicity and Carcinogenicity (C20005) of Ginseng (50647-08-0) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C20203) of Green Tea Extract (GREENTEAEXTR) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C60015) of Turmeric, Oleoresin (Curcumin) (8024-37-1) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in B6C3F1 Mice Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Special Evaluation of the Toxicity (C99031) of Ginkgo Biloba Extract (90045-36-6) in F344/N Rats Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Actaea racemosa (Black Cohosh) XRM in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058V
Summary Data
Genetic Toxicity Evaluation of Aloe Vera Charcoal Filtered Whole Leaf Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03042
Summary Data
Genetic Toxicity Evaluation of Aloe Vera Gel in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A20251
Summary Data
Genetic Toxicity Evaluation of Aloe Vera Gel in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99056
Summary Data
Genetic Toxicity Evaluation of Aloe Vera Whole Leaf Extract (Native) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03041
Summary Data
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44526
Summary Data
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A50684
Summary Data
Genetic Toxicity Evaluation of Annatto in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A82879
Summary Data
Genetic Toxicity Evaluation of Bixin (6983-79-5) in Micronucleus Study F68597 in B6C3F1 Mice
Genetic Toxicity Evaluation of Bixin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A24885
Summary Data
Genetic Toxicity Evaluation of Bixin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42709
Summary Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058 in Wistar Han Rats
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058B in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058C in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058E in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (BCE_3012781) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Y
Summary Data
Genetic Toxicity Evaluation of Black Cohosh (BCE_BCO2.5-A2401090310) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058X
Summary Data
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE2) (BCE_TP20141210-R) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Z
Summary Data
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A13815
Summary Data
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058D
Summary Data
Genetic Toxicity Evaluation of Cedarwood Oil (8000-27-9) in Micronucleus Study A16009 in B6C3F1 Mice
Genetic Toxicity Evaluation of Cedarwood Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A51043
Summary Data
Genetic Toxicity Evaluation of Curcumin (458-37-7) in Micronucleus Study A43540 in F344 Rats
Genetic Toxicity Evaluation of Curcumin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 489345
Summary Data
Genetic Toxicity Evaluation of Curcumin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A73195
Summary Data
Genetic Toxicity Evaluation of Dong Quai in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A72844
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067BIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067C
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067CIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067E
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067EIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067FIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067GIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067H
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067HIR
Summary Data
Genetic Toxicity Evaluation of Echinacea Purpurea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99067IR
Summary Data
Genetic Toxicity Evaluation of Garcinia Cambogia Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G05016
Summary Data
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G03008 in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050 in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050B in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050C in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050D in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba (GINKGOBILOBAEXTRACT), Goldenseal (GOLDENSEALEXTRACT) and Green Tea Extract (GREENTEAEXTR) in Micronucleus Study G99050E in F344/NTac Rats
Genetic Toxicity Evaluation of Ginkgo Biloba Extract (90045-36-6) in Micronucleus Study A97646 in B6C3F1 Mice
Genetic Toxicity Evaluation of Ginkgo Biloba Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A33386
Summary Data
Genetic Toxicity Evaluation of Ginseng (50647-08-0) in Micronucleus Study A82446 in B6C3F1 Mice
Genetic Toxicity Evaluation of Ginseng in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A04849
Summary Data
Genetic Toxicity Evaluation of Ginseng in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A16457
Summary Data
Genetic Toxicity Evaluation of Goldenseal Root Powder (GOLDENSEALRT) in Micronucleus Study A21831 in B6C3F1 Mice
Genetic Toxicity Evaluation of Goldenseal Root Powder in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A83314
Summary Data
Genetic Toxicity Evaluation of Grape Seed Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A03106
Summary Data
Genetic Toxicity Evaluation of Green Tea Extract (GREENTEAEXTR) in Micronucleus Study A70207 in B6C3F1 Mice
Genetic Toxicity Evaluation of Green Tea Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A43286
Summary Data
Genetic Toxicity Evaluation of Gum Guggul Extract (GUMGUGGULEXT) in Micronucleus Study G05066 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Gum Guggul Extract (GUMGUGGULEXT) in Micronucleus Study G05066B in B6C3F1 Mice
Genetic Toxicity Evaluation of Juglone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A50290
Summary Data
Genetic Toxicity Evaluation of Kava Kava Extract (9000-38-8) in Micronucleus Study A53705 in B6C3F1 Mice
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A00186
Summary Data
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A88186
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract (84604-20-6) in Micronucleus Study A73501 in B6C3F1 Mice
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A21904
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41673
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42260
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44499
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A78884
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99059
Summary Data
Genetic Toxicity Evaluation of Norbixin (cis/trans Mixture) (542-40-5) in Micronucleus Study F34414 in B6C3F1 Mice
Genetic Toxicity Evaluation of Norbixin (cis/trans Mixture) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A63936
Summary Data
Genetic Toxicity Evaluation of Pine Bark Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A91384
Summary Data
Genetic Toxicity Evaluation of Safflower Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 469522
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) (8013-11-4) in Micronucleus Study GEMT28 in P53 +/- (C57BL/6) Mice
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 840294
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A09328
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A10901
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study GEMT28B
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Genetic Toxicity Evaluation of Sennoside A in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G01053
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Genetic Toxicity Evaluation of Turmeric, Oleoresin (Curcumin) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 857432
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Genetic Toxicity Evaluation of Valerian (Valeriana officinalis L.) Root Oil in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A66100
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345B
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345C
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345D
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345E
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345F
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345G
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345H
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345I
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345J
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345K
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Genetic Toxicity Evaluation of Valerian (Various) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10345L
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Genetic Toxicity Evaluation of Valerian Root Extract (8057-49-6) in Micronucleus Study G09042 in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE3) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058W
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Other NTP Studies


Prenatal Developmental Toxicity Pilot Study (TRP98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Prenatal Developmental Toxicity Pilot Study (TRP99007) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed
Prenatal Developmental Toxicity Study (TER98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Prenatal Developmental Toxicity Study (TER99004) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed
Toxicokinetic Evaluation (K99050) of Ginkgo biloba (DTXSID8031366) in Rat

Other Studies


4-Week Immunotoxicity Evaluation (IMM20701) of Gum Guggul 2.5% granules (GUMGUGGULEXT) in Female B6C3F1 Mice Exposed via Gavage
Statistical Tables
Individual Animal Data