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Aloe vera leaf extract (ALOEVLEAFEXT)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Aloe vera leaf extract (ALOEVLEAFEXT).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Aloe vera leaf extract (ALOEVLEAFEXT). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-577 Toxicology and Carcinogenesis Studies of a Nondecolorized Whole Leaf Extract of Aloe Barbadensis Miller (Aloe Vera) (CASRN ALOEVLEAFEXT) in F344/N Rats and B6C3F1 Mice (Drinking Water Study)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/NCTR Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1/NCTR Mice Exposed via Dosed Water
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Aloe Vera Whole Leaf Extract (Native) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03041
Summary Data