Aloe vera leaf extract (ALOEVLEAFEXT)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7030694
Publications
TR-577
Toxicology and Carcinogenesis Studies of a Nondecolorized Whole Leaf Extract of Aloe Barbadensis Miller (Aloe Vera) (CASRN ALOEVLEAFEXT) in F344/N Rats and B6C3F1 Mice (Drinking Water Study)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
3-Month Evaluation of the Toxicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in F344/NCTR Rats Exposed via Dosed Water
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (69 kB)
- P04 - Neoplasms by Individual Animal (813 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (71 kB)
- P40 - Survival Curves (87 kB)
Individual Animal Data
- Female Individual Animal Neoplastic Pathology Data (218 kB)
- Female Individual Animal Non Neoplastic Pathology Data (972 kB)
- Female Individual Animal Organ Weight Data (54 kB)
- Female Individual Animal Survival Data (32 kB)
- Male Individual Animal Neoplastic Pathology Data (385 kB)
- Male Individual Animal Non Neoplastic Pathology Data (998 kB)
- Male Individual Animal Organ Weight Data (54 kB)
- Male Individual Animal Survival Data (32 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20116B) of Aloe Vera Whole Leaf Extract (Native) (ALOEVLEAFEXT) in B6C3F1/NCTR Mice Exposed via Dosed Water
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (59 kB)
- P04 - Neoplasms by Individual Animal (771 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (858 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (60 kB)
- P40 - Survival Curves (84 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (621 kB)
- Female Individual Animal Neoplastic Pathology Data (215 kB)
- Female Individual Animal Non Neoplastic Pathology Data (740 kB)
- Female Individual Animal Organ Weight Data (55 kB)
- Female Individual Animal Survival Data (32 kB)
- Male Individual Animal Body Weight Data (633 kB)
- Male Individual Animal Neoplastic Pathology Data (124 kB)
- Male Individual Animal Non Neoplastic Pathology Data (573 kB)
- Male Individual Animal Organ Weight Data (55 kB)
- Male Individual Animal Survival Data (32 kB)
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
1-Year Evaluation of the Toxicity (C20406) of Aloe Phototoxicity Studies (ALOEPHOTOTOX) in SKH-1/NCTR Mice Exposed via Topical Application
Pathology Tables
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Aloe Vera Whole Leaf Extract (Native) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03041
Summary Data
- G06 - Ames Summary Data (92 KB)