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TOX-92: 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2)

Citation Information

NTP. TOX-92: 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-ethanone (54464-57-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

TOX-92 NTP Technical Report on the Toxicity Studies of Octahydro-tetramethyl-naphthalenyl-ethanone (OTNE) Administered Dermally to F344/NTac Rats and B6C3F1/N Mice

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C20307) of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) (54464-57-2) in F344/NTac Rats Exposed via Topical Application

Study Tables

E03 - Growth Curves (63 kB)
E04 - Mean Body Weights and Survival Table (23 kB)
E05 - Clinical Observations Summary (19 kB)
E09 - Summary of Dermal Clinical Observations at Site Of Application (12 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (56 kB)
P04 - Neoplasms by Individual Animal (269 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (57 kB)
P08 - Statistical Analysis of Primary Tumors (Untreated + High Dose) (111 kB)
P08 - Statistical Analysis of Primary Tumors (Without High Dose) (104 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (283 kB)
P14 - Individual Animal Pathology Data (343 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (58 kB)
P40 - Survival Curves (59 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (40 kB)
Female Individual Animal Clinical Observations (3 kB)
Female Individual Animal Non Neoplastic Pathology Data (48 kB)
Female Individual Animal Organ Weight Data (30 kB)
Female Individual Animal Survival Data (13 kB)
Male Individual Animal Body Weight Data (40 kB)
Male Individual Animal Clinical Observations (3 kB)
Male Individual Animal Non Neoplastic Pathology Data (51 kB)
Male Individual Animal Organ Weight Data (30 kB)
Male Individual Animal Survival Data (13 kB)

3-Month Evaluation of the Toxicity (C20307) of Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super; OTNE) (54464-57-2) in B6C3F1 Mice Exposed via Topical Application

Study Tables

E03 - Growth Curves (66 kB)
E04 - Mean Body Weights and Survival Table (23 kB)
E05 - Clinical Observations Summary (19 kB)
E09 - Summary of Dermal Clinical Observations at Site Of Application (15 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (56 kB)
P04 - Neoplasms by Individual Animal (275 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (57 kB)
P08 - Statistical Analysis of Primary Tumors (Untreated + High Dose) (109 kB)
P08 - Statistical Analysis of Primary Tumors (Without High Dose) (107 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (291 kB)
P14 - Individual Animal Pathology Data (351 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (58 kB)
P40 - Survival Curves (58 kB)

Individual Animal Data

Female Individual Animal Body Weight Data (39 kB)
Female Individual Animal Clinical Observations (24 kB)
Female Individual Animal Non Neoplastic Pathology Data (92 kB)
Female Individual Animal Organ Weight Data (30 kB)
Female Individual Animal Survival Data (13 kB)
Male Individual Animal Body Weight Data (39 kB)
Male Individual Animal Clinical Observations (30 kB)
Male Individual Animal Neoplastic Pathology Data (2 kB)
Male Individual Animal Non Neoplastic Pathology Data (87 kB)
Male Individual Animal Organ Weight Data (30 kB)
Male Individual Animal Survival Data (13 kB)