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TR-300: 3-Chloro-2-methylpropene (563-47-3)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-300: 3-Chloro-2-methylpropene (563-47-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-300: 3-Chloro-2-methylpropene (563-47-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-300: 3-Chloro-2-methylpropene (563-47-3).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Weakly Positive

Citation Information


NTP. TR-300: 3-Chloro-2-methylpropene (563-47-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-300 Toxicology and Carcinogenesis Studies of 3-Chloro-2-methylpropene (Technical grade containing 5% Dimethylvinyl chloride) (CASRN 563-47-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloro-2-methylpropene (563-47-3) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloro-2-methylpropene (563-47-3) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloro-2-methylpropene (563-47-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloro-2-methylpropene (563-47-3) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 3-Chloro-2-methylpropene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 154361
Summary Data
Genetic Toxicity Evaluation of 3-Chloro-2-methylpropene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 701637
Summary Data
Genetic Toxicity Evaluation of 3-Chloro-2-methylpropene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 933790
Summary Data