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TR-317: Chlorpheniramine maleate (113-92-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-317: Chlorpheniramine maleate (113-92-8).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-317: Chlorpheniramine maleate (113-92-8).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-317: Chlorpheniramine maleate (113-92-8).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-317: Chlorpheniramine maleate (113-92-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-317: Chlorpheniramine maleate (113-92-8).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. TR-317: Chlorpheniramine maleate (113-92-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-317 Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorpheniramine Maleate (113-92-8) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorpheniramine Maleate (113-92-8) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorpheniramine Maleate (113-92-8) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorpheniramine Maleate (113-92-8) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Chlorpheniramine Maleate (113-92-8) in Micronucleus Study A45472 in B6C3F1 Mice
Genetic Toxicity Evaluation of Chlorpheniramine Maleate (113-92-8) in Micronucleus Study A98719 in F344 Rats
Genetic Toxicity Evaluation of Chlorpheniramine Maleate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 543950
Summary Data