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TR-350: Tribromomethane (75-25-2)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to TR-350: Tribromomethane (75-25-2).
Rodent Cytogenetics
CA SCE
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-350: Tribromomethane (75-25-2).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-350: Tribromomethane (75-25-2).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-350: Tribromomethane (75-25-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-350: Tribromomethane (75-25-2).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-350: Tribromomethane (75-25-2).
Bacterial Mutagenicity
View
  • Equivocal
View
  • Negative
View
  • Positive
View
  • Equivocal

Citation Information

NTP. TR-350: Tribromomethane (75-25-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-350 Toxicology and Carcinogenesis Studies of Tribromomethane (Bromoform) (CASRN 75-25-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C55130) of Tribromomethane (75-25-2) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55130) of Tribromomethane (75-25-2) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Tribromomethane (75-25-2) in Micronucleus Study 244282 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Tribromomethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 312147
Summary Data
Genetic Toxicity Evaluation of Tribromomethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 445991
Summary Data
Genetic Toxicity Evaluation of Tribromomethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 460994
Summary Data
Genetic Toxicity Evaluation of Tribromomethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 871929
Summary Data