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TR-423: 3,4-Dihydrocoumarin (119-84-6)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
  • Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-423: 3,4-Dihydrocoumarin (119-84-6).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-423: 3,4-Dihydrocoumarin (119-84-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-423: 3,4-Dihydrocoumarin (119-84-6).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. TR-423: 3,4-Dihydrocoumarin (119-84-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-423 Toxicology and Carcinogenesis Studies of 3,4-Dihydrocoumarin (CASRN 119-84-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C55890B) of 3,4-Dihydrocoumarin (119-84-6) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55890B) of 3,4-Dihydrocoumarin (119-84-6) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 3,4-Dihydrocoumarin (119-84-6) in Micronucleus Study A43806 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 3,4-Dihydrocoumarin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 911172
Summary Data