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TR-453: Nickel subsulfide (12035-72-2)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-453: Nickel subsulfide (12035-72-2).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-453: Nickel subsulfide (12035-72-2).
Bacterial Mutagenicity
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  • Equivocal

Citation Information


NTP. TR-453: Nickel subsulfide (12035-72-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-453 Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CASRN 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C61654) of Nickel Subsulfide (12035-72-2) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61654) of Nickel Subsulfide (12035-72-2) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Nickel Subsulfide (12035-72-2) in Micronucleus Study A50848 in B6C3F1 Mice
Genetic Toxicity Evaluation of Nickel Subsulfide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 498230
Summary Data