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TR-461: Nitromethane (75-52-5)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-461: Nitromethane (75-52-5).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-461: Nitromethane (75-52-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-461: Nitromethane (75-52-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. TR-461: Nitromethane (75-52-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-461 Toxicology and Carcinogenesis Studies of Nitromethane (CASRN 75-52-5) in F344 Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61927) of Nitromethane (75-52-5) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C61927) of Nitromethane (75-52-5) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61927) of Nitromethane (75-52-5) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61927) of Nitromethane (75-52-5) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Nitromethane (75-52-5) in Micronucleus Study A55749 in B6C3F1 Mice
Genetic Toxicity Evaluation of Nitromethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 860172
Summary Data