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TR-461: Nitromethane (75-52-5)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-461: Nitromethane (75-52-5).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-461: Nitromethane (75-52-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-461: Nitromethane (75-52-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. TR-461: Nitromethane (75-52-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-461 Toxicology and Carcinogenesis Studies of Nitromethane (CASRN 75-52-5) in F344 Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C61927) of Nitromethane (75-52-5) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C61927) of Nitromethane (75-52-5) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C61927) of Nitromethane (75-52-5) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C61927) of Nitromethane (75-52-5) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nitromethane (75-52-5) in Micronucleus Study A55749 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Nitromethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 860172
Summary Data