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4-Vinylcyclohexene (100-40-3)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Inadequate Study, Male, Rats
View
  • Inadequate Study, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Inadequate Study, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 4-Vinylcyclohexene (100-40-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Vinylcyclohexene (100-40-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Vinylcyclohexene (100-40-3).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 4-Vinylcyclohexene (100-40-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-303 Toxicology and Carcinogenesis Studies of 4-Vinylcyclohexene (CASRN 100-40-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 4-Vinylcyclohexene (100-40-3) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 4-Vinylcyclohexene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 609542
Summary Data
Genetic Toxicity Evaluation of 4-Vinylcyclohexene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 777152
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0084) of 4-Vinylcyclohexene (100-40-3) in F344 Rats and B6C3F1 Mice Exposed via Gavage and Dermal Administration