Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Boric acid (10043-35-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020194

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Boric acid (10043-35-3).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Boric acid (10043-35-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Boric acid (10043-35-3).
Bacterial Mutagenicity
View
  • Negative
View
  • Equivocal

Citation Information

NTP. Boric acid (10043-35-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-324 Toxicology and Carcinogenesis Studies of Boric Acid (CASRN 10043-35-3) in B6C3F1 Mice (Feed Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Final Report on the CNS Developmental Toxicity of Boric Acid in Sprague-Dawley CD Rats Exposed on Gestation Days 14-17
Final Report on the CNS Developmental Toxicity of Boric Acid in Sprague-Dawley CD Rats Exposed on Gestation Days 14-17
Final Report on the CNS Developmental Toxicity of Boric Acid in Sprague-Dawley CD Rats Exposed on Gestation Days 6-15
CNS Developmental Toxicity of Boric Acid (CASRN 10043-35-3) in Sprague-Dawley CD® Rats Exposed on Gestation Days 6-15. Volume II
Final Report on the CNS Developmental Toxicity of Boric Acid in Sprague-Dawley CD Rats Exposed on Gestation Days 6-15
Final Report on the Developmental Toxicity Evaluation of Boric Acid Administered in Feed to CD-1 Mice on Gestational Days 0 to 17
Final Report on the Developmental Toxicity Evaluation of Boric Acid Administered in Feed to Sprague-Dawley (CD) Rats on Gestational Days 0-20 or 6-15
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Boric Acid (10043-35-3) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Boric Acid (10043-35-3) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Boric Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 683471
Summary Data
Genetic Toxicity Evaluation of Boric Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 789471
Summary Data

Other NTP Studies

Prenatal Developmental Toxicity Study (TER89027) of Boric Acid (10043-35-3) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER89028) of Boric Acid (10043-35-3) in Swiss CD-1 Mice Exposed via Dosed Feed
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER90003) of Boric Acid (10043-35-3) in New Zealand White Rabbits Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER90123) of Boric Acid (10043-35-3) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER93138) of Boric Acid (10043-35-3) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data

DTT Data Collections