Di(2-ethylhexyl)adipate (103-23-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020606
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Rodent Cytogenetics |
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CA |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
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Bacterial Mutagenicity |
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Publications
TR-212
Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and B6C3F1 Mice (Feed Study)
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Di(2-ethylhexyl)adipate (103-23-1) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Di(2-ethylhexyl)adipate (103-23-1) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Di(2-ethylhexyl)adipate (103-23-1) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Di(2-ethylhexyl)adipate (103-23-1) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Di(2-ethylhexyl)adipate (103-23-1) in Micronucleus Study 719908 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Di(2-ethylhexyl)adipate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 648372
Summary Data
- G06 - Ames Summary Data (135 KB)
Genetic Toxicity Evaluation of Di(2-ethylhexyl)adipate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 947372
Summary Data
- G06 - Ames Summary Data (131 KB)
Genetic Toxicity Evaluation of Di(2-ethylhexyl)adipate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 963935
Summary Data
- G06 - Ames Summary Data (61 KB)