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4-Vinyl-1-cyclohexene diepoxide (106-87-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020604

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. 4-Vinyl-1-cyclohexene diepoxide (106-87-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-362 Toxicology and Carcinogenesis Studies of 4-Vinyl-1-cyclohexene Diepoxide (CASRN 106-87-6) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C60139A) of 4-Vinyl-1-cyclohexene Diepoxide (106-87-6) in F344/N Rats Exposed via Topical Application
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C60139A) of 4-Vinyl-1-cyclohexene Diepoxide (106-87-6) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 4-Vinyl-1-cyclohexene Diepoxide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 708500
Summary Data

NTP Data Collections