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Allyl glycidyl ether (106-92-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9039232

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Allyl glycidyl ether (106-92-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Allyl glycidyl ether (106-92-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Allyl glycidyl ether (106-92-3).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Allyl glycidyl ether (106-92-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Allyl glycidyl ether (106-92-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-376 Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CASRN 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalation Studies)
Canter, D.A., Zeiger, E., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Comparative mutagenicity of aliphatic epoxides in Salmonella Mutation Res. Vol. 172 (1986) 105-138
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C56666) of Allyl Glycidyl Ether (106-92-3) in Osborne-Mendel Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C56666) of Allyl Glycidyl Ether (106-92-3) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Allyl Glycidyl Ether (106-92-3) in Micronucleus Study 446759 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Allyl Glycidyl Ether (106-92-3) in Micronucleus Study A65776 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Allyl Glycidyl Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 838866
Summary Data

NTP Data Collections