COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Tetrachlorophthalic anhydride (117-08-8)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Tetrachlorophthalic anhydride (117-08-8).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Tetrachlorophthalic anhydride (117-08-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Tetrachlorophthalic anhydride (117-08-8).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Tetrachlorophthalic anhydride (117-08-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Tetrachlorophthalic anhydride (117-08-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-28 Toxicity Studies of Tetrachlorophthalic Anhydride (CASRN 117-08-8) Administered by Gavage to F344/N Rats and B6C3F1Mice
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61585) of Tetrachlorophthalic Anhydride (117-08-8) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C61585) of Tetrachlorophthalic Anhydride (117-08-8) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C61585) of Tetrachlorophthalic Anhydride (117-08-8) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C61585) of Tetrachlorophthalic Anhydride (117-08-8) in B6C3F1 Mice Exposed via Gavage