U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

N,N-Dimethylaniline (121-69-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020507


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Some Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • Equivocal Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N,N-Dimethylaniline (121-69-7).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N,N-Dimethylaniline (121-69-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N,N-Dimethylaniline (121-69-7).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. N,N-Dimethylaniline (121-69-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-360 Toxicology and Carcinogenesis Studies of N,N-Dimethylaniline (CASRN 121-69-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Female B6C3F1 Mice Exposed via Gavage