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N,N-Dimethylaniline (121-69-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020507

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Some Evidence, Male, Rats
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  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • No Evidence, Male, Mice
View
  • Equivocal Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N,N-Dimethylaniline (121-69-7).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N,N-Dimethylaniline (121-69-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N,N-Dimethylaniline (121-69-7).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. N,N-Dimethylaniline (121-69-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-360 Toxicology and Carcinogenesis Studies of N,N-Dimethylaniline (CASRN 121-69-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Male F344 Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Female F344 Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Male B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N-Dimethylaniline (121-69-7) in Female B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of N,N-Dimethylaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 840758
Summary Data

NTP Data Collections