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Tris(Chloropropyl)phosphate (13674-84-5)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Tris(Chloropropyl)phosphate (13674-84-5).
Micronucleus - Mice
View
  • Male: Positive
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Tris(Chloropropyl)phosphate (13674-84-5).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Tris(Chloropropyl)phosphate (13674-84-5).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Tris(Chloropropyl)phosphate (13674-84-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


DART-01 Prenatal Developmental Toxicity Studies of Tris(chloropropyl) Phosphate in Sprague Dawley (Hsd:Sprague Dawley SD) Rats (Gavage Studies)
Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes William M. Gwinn, Scott S. Auerbach, Fred Parham, Matthew D. Stout, Suramya Waidyanatha, Esra Mutlu, Brad Collins, Richard S Paules, B. Alex Merrick, Stephen Ferguson, Sreenivasa Ramaiahgari, John R. Bucher, Barney Sparrow, Heather Toy, Jenni Gorospe, Nick Machesky, Ruchir R. Shah, Michele R. Balik-Meisner, Deepak Mav, Dhiral P. Phadke, Georgia Roberts, Michael J. DeVito


CEBS DOI: https://doi.org/10.22427/NTP-DATA-002-00058-0002-0000-7
GEO No.: GSE147072: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE147072
BioProject No.: PRJNA612884: https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA612884
SRA No.: SRP253005: https://www.ncbi.nlm.nih.gov/sra?term=SRP253005

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate (13674-84-5) in Micronucleus Study G20263 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate (13674-84-5) in Micronucleus Study G20263B in B6C3F1 Mice
Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 815918
Summary Data
Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G20263C
Summary Data

Other NTP Studies


Evaluation of the Prenatal Development Toxicity (R20263B) of tris(Chloropropyl)phosphate (TCPP) (13674-84-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Evaluation of the Prenatal Developmental Toxicity Dose Range Finding Study (R20263) of tris(Chloropropyl)phosphate (TCPP) (13674-84-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Screen for Developmental Toxicity in Zebrafish- Study 1
Results