Benzyl acetate (140-11-4)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020151
Study Results
Chronic Bioassay Level of Evidence
| Rats | |
|---|---|
View
|
|
View
|
|
View
|
|
| Mice | |
|---|---|
View
|
|
View
|
|
View
|
|
Genetic Toxicology
| Rodent Cytogenetics | |
|---|---|
| CA | SCE |
|
|
| Micronucleus - Mice |
|---|
View
|
View
|
| Mammalian Cell Mutagenicity |
|---|
View
|
View
|
| Mammalian Cell Cytogenetics | |
|---|---|
| CA | SCE |
|
|
| Drosophila Germ Cell Mutagenicity |
|---|
| SLRL |
|
| Bacterial Mutagenicity |
|---|
View
|
Publications
TR-250
Toxicology and Carcinogenesis Studies of Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
TR-431
Toxicology and Carcinogenesis Studies of Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1 Mice Feed Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Study Data
Toxicity and Carcinogenicity Studies
18-33 Day Evaluation of the Toxicity (C93017) of Benzyl Acetate + Glycine Combination Study (GLYCINEBENZA) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C06508B) of Benzyl Acetate (140-11-4) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C06508B) of Benzyl Acetate (140-11-4) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzyl Acetate (140-11-4) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzyl Acetate (140-11-4) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzyl Acetate (140-11-4) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzyl Acetate (140-11-4) in Female B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C06508B) of Benzyl Acetate (140-11-4) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C06508B) of Benzyl Acetate (140-11-4) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Benzyl Acetate (140-11-4) in Micronucleus Study 432849 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Benzyl Acetate (140-11-4) in Micronucleus Study A89285 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Benzyl Acetate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 883303
Summary Data
- G06 - Ames Summary Data (130 KB)