U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

2,4-Hexadienal (142-83-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID20859279


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2,4-Hexadienal (142-83-6).
Micronucleus - Mice
View
  • Male: Equivocal
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 2,4-Hexadienal (142-83-6).
Micronucleus - Rats
View
  • Male: Equivocal
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,4-Hexadienal (142-83-6).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive

Citation Information


NTP. 2,4-Hexadienal (142-83-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-509 Toxicology and Carcinogenesis Studies of 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83-6; 11% cis,trans Isomer in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C93023) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C93023) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C93023B) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A11915 in F344 Rats
Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A53565 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A84857 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2,4-Hexadienal in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A46849
Summary Data
Genetic Toxicity Evaluation of 2,4-Hexadienal in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A98429
Summary Data