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TR-509: 2,4-Hexadienal (142-83-6)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-509: 2,4-Hexadienal (142-83-6).
Micronucleus - Rats
View
  • Male: Equivocal
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-509: 2,4-Hexadienal (142-83-6).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Equivocal
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-509: 2,4-Hexadienal (142-83-6).
Bacterial Mutagenicity
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  • Positive
View
  • Positive

Citation Information


NTP. TR-509: 2,4-Hexadienal (142-83-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-509 Toxicology and Carcinogenesis Studies of 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83-6; 11% cis,trans Isomer in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C93023) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C93023) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C93023B) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C93023B) of 2,4-Hexadienal (142-83-6) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C93023B) of 2,4-Hexadienal (142-83-6) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A11915 in F344 Rats
Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A53565 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2,4-Hexadienal (142-83-6) in Micronucleus Study A84857 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2,4-Hexadienal in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A46849
Summary Data
Genetic Toxicity Evaluation of 2,4-Hexadienal in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A98429
Summary Data