U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

phenol,4,4-(2,2,2-triflouro-1-(trifluromethyl)ethylidene) (1478-61-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7037717


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to phenol,4,4-(2,2,2-triflouro-1-(trifluromethyl)ethylidene) (1478-61-1).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to phenol,4,4-(2,2,2-triflouro-1-(trifluromethyl)ethylidene) (1478-61-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. phenol,4,4-(2,2,2-triflouro-1-(trifluromethyl)ethylidene) (1478-61-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


DART-08 Prenatal Development Studies of Bisphenol AF in Sprague Dawley (Sprague Dawley SD) Rats (Dosed Feed Studies) CASRN: 1478-61-1
Waidyanatha S, SR Black, CR Croutch, BJ Collins, MAR Silinski, S Kerns, V Sutherland, V Godfrey Robinson, K Aillon, RA Fernando, E Mutlu and TR Fennell. Comparative toxicokinetics of bisphenol S and bisphenol AF in male rats and mice following repeated exposure via feed [Journal Article] Xenobiotica (2020) [In Press]
Binding of Bisphenol A, Bisphenol AF, and Bisphenol S on the Androgen Receptor: Coregulator Recruitment and Stimulation of Potential Interaction Sites Lalith Perera, Yin Li, Laurel A. Coons, Rene Houtman, Rinie van Beuningen, Bonnie Goodwin, Scott S. Auerbach, and Christina T. Teng.
Toxicology in Vitro (2017) DOI: https://doi.org/10.1016/j.tiv.2017.07.020 PMID: 28751236
An investigation of systemic exposure to bisphenol AF during critical periods of development in the rat Suramya Waidyanatha, Bradley J. Collins, Helen Cunny, Kristin Aillon, Felicia Riordan, Katie Turner, and Vicki Sutherland

DOI: https://doi.org/10.22427/NTP-DATA-002-03263-0010-0000-7

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Bisphenol AF (1478-61-1) in Micronucleus Study G08002B in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Bisphenol AF in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G08002
Summary Data

Other NTP Studies


Modified One Generation (MOG) Dose Range Finding Toxicity Study (MOG08002) of Bisphenol AF (1478-61-1) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Modified One Generation (MOG) Toxicity Study (MOG08002B) of Bisphenol AF (1478-61-1) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Study Tables
Individual Animal Data
Toxicokinetic Evaluation (K08002C) of Bisphenol AF (DTXSID7037717) in Rat and Mouse
Toxicokinetic Evaluation (K08002D) of Bisphenol AF (DTXSID7037717) in Rat and Mouse