Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Sodium diethyldithiocarbamate (148-18-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3022956

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Sodium diethyldithiocarbamate (148-18-5).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Sodium diethyldithiocarbamate (148-18-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Sodium diethyldithiocarbamate (148-18-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Sodium diethyldithiocarbamate (148-18-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-172 Bioassay of Sodium Diethyldithiocarbamate for Possible Carcinogenicity (CASRN 148-18-5)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Sodium Diethyldithiocarbamate (148-18-5) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Sodium Diethyldithiocarbamate (148-18-5) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Sodium Diethyldithiocarbamate (148-18-5) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Sodium Diethyldithiocarbamate (148-18-5) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Sodium Diethyldithiocarbamate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 965008
Summary Data

DTT Data Collections