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Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3032129


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-85 Toxicity Studies of Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (CASRN 21850-44-2) Administered by Gavage to F344/NTac Rats and B6C3F1/N Mice
Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat Keith R Shockley, Michelle C Cora, David E Malarkey, Daven Jackson-Humbles, Molly Vallant, Brad J Collins, Esra Mutlu, Veronica G Robinson, Surayma Waidyanatha, Amy Zmarowski, Nicholas Machesky, Jamie Richey, Sam Harbo, Emily Cheng, Kristin Patton, Barney Sparrow, June K Dunnick

Toxicology Letters (2020) DOI: https://doi.org/10.1016/j.toxlet.2020.07.016 PMID: 32679240

GEO: GSE153366

Study Data


Toxicity and Carcinogenicity Studies


5-Day Evaluation of the Toxicity (C02047-01) of Tetrabromobisphenol A-bis(2,3-dibromopropyl ether)(21850-44-2) in Sprague Dawley Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20321) of Tetrabromobisphenol A-bis(2,3-dibromopropyl Ether) (21850-44-2) in F344/NTac Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20321) of Tetrabromobisphenol A-bis(2,3-dibromopropyl Ether) (21850-44-2) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Tetrabromobisphenol A-bis(2,3-Dibromopropyl Ether) (21850-44-2) in Micronucleus Study A90104 in B6C3F1 Mice
Genetic Toxicity Evaluation of Tetrabromobisphenol A-bis(2,3-Dibromopropyl Ether) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44427
Summary Data