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Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3032129


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2).
Micronucleus - Mice
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  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (21850-44-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-85 Toxicity Studies of Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (CASRN 21850-44-2) Administered by Gavage to F344/NTac Rats and B6C3F1/N Mice
Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, Sparrow B, Dunnick JK. Transcriptomic data from the rat liver after five days of exposure to legacy or emerging brominated flame retardants. Data Brief. 2020 Aug 5;32:106136. doi: 10.1016/j.dib.2020.106136. eCollection 2020 Oct. PMID: 32904430
Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat Keith R Shockley, Michelle C Cora, David E Malarkey, Daven Jackson-Humbles, Molly Vallant, Brad J Collins, Esra Mutlu, Veronica G Robinson, Surayma Waidyanatha, Amy Zmarowski, Nicholas Machesky, Jamie Richey, Sam Harbo, Emily Cheng, Kristin Patton, Barney Sparrow, June K Dunnick

Toxicology Letters (2020) DOI: https://doi.org/10.1016/j.toxlet.2020.07.016 PMID: 32679240

GEO: GSE153366

Study Data


Toxicity and Carcinogenicity Studies


5-Day Evaluation of the Toxicity (C02047-01) of Tetrabromobisphenol A-bis(2,3-dibromopropyl ether)(21850-44-2) in Sprague Dawley Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20321) of Tetrabromobisphenol A-bis(2,3-dibromopropyl Ether) (21850-44-2) in F344/NTac Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20321) of Tetrabromobisphenol A-bis(2,3-dibromopropyl Ether) (21850-44-2) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Tetrabromobisphenol A-bis(2,3-Dibromopropyl Ether) (21850-44-2) in Micronucleus Study A90104 in B6C3F1 Mice
Genetic Toxicity Evaluation of Tetrabromobisphenol A-bis(2,3-Dibromopropyl Ether) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44427
Summary Data