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Riddelliine (23246-96-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4026006


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Riddelliine (23246-96-0).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Riddelliine (23246-96-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Riddelliine (23246-96-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Riddelliine (23246-96-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-508 Toxicology and Carcinogenesis Studies of Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
TOX-27 Toxicity Studies of Riddelliine (CASRN 23246-96-0) Administered by Gavage to F344 Rats and B6C3F1Mice.
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


24 - 72-Hour Evaluation of the Toxicity (C20328) of Riddelliine (23246-96-0) in F344 Rats Exposed via Gavage. NTP Special Study
3 - 24-Hour Evaluation of the Toxicity (C20328) of Riddelliine (23246-96-0) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C61358B) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C61358B) of Riddelliine (23246-96-0) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Riddelliine (23246-96-0) in Micronucleus Study A52780 in B6C3F1 Mice
Genetic Toxicity Evaluation of Riddelliine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 532340
Summary Data