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Riddelliine (23246-96-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4026006

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Riddelliine (23246-96-0).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Riddelliine (23246-96-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Riddelliine (23246-96-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Riddelliine (23246-96-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-508 Toxicology and Carcinogenesis Studies of Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
TOX-27 Toxicity Studies of Riddelliine (CASRN 23246-96-0) Administered by Gavage to F344 Rats and B6C3F1Mice.
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data

Protocol

Toxicity and Carcinogenicity Studies

24 - 72-Hour Evaluation of the Toxicity (C20328) of Riddelliine (23246-96-0) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
Clinical Chemistry Reports
3 - 24-Hour Evaluation of the Toxicity (C20328) of Riddelliine (23246-96-0) in F344 Rats Exposed via Gavage. NTP Special Study
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C61358B) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C61358B) of Riddelliine (23246-96-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C61358C) of Riddelliine (23246-96-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Riddelliine (23246-96-0) in Micronucleus Study A52780 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Riddelliine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 532340
Summary Data

DTT Data Collections