Potassium perfluorohexanesulfonate (3871-99-6)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3037709
Publications
TOX-96
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
Toxicokinetics of Perfluorobutane Sulfonate (PFBS), Perfluorohexane-1-Sulphonic Acid (PFHxS), and Perfluorooctane Sulfonic Acid (PFOS) in Male and Female Hsd:Sprague Dawley SD Rats after Intravenous and Gavage Administration
Huang M.C., Dzierlenga A., Robinson V.G, Waidyanatha S, DeVito M.J, Eifrid M.A, Granville C.A., Gibbs S.T, Blystone C.R
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3
Unraveling Human Hepatocellular Responses to PFAS and Aqueous Film-Forming Foams (AFFFs) for Molecular Hazard Prioritization and In Vivo Translation
Kevin A. Mauge-Lewis1,‡, Sreenivasa C. Ramaiahgari1,‡, Scott S. Auerbach1, Georgia K. Roberts1, Suramya Waidyanatha1, Suzanne E Fenton1, Dhiral P. Phadke2, Michele R. Balik-Meisner2, Arpit Tandon2, Deepak Mav2, Brian Howard2, Ruchir Shah2, Barney Sparrow3, Jenni Gorospe3, Stephen S. Ferguson1
‡These authors equally contributed to this study.
1Division of Translational Toxicology at the National Institute for Environmental Sciences, Research Triangle Park, North Carolina
2Sciome, Research Triangle Park, North Carolina
3Battelle, Columbus, Ohio
Environmental Science and Technology, (2025) DOI: https://doi.org/10.1021/acs.est.4c10595 PMID: 398893674 PMCID: PMC11823446
DOI: https://doi.org/10.22427/NTP-DATA-500-017-001-000-4
‡These authors equally contributed to this study.
1Division of Translational Toxicology at the National Institute for Environmental Sciences, Research Triangle Park, North Carolina
2Sciome, Research Triangle Park, North Carolina
3Battelle, Columbus, Ohio
Environmental Science and Technology, (2025) DOI: https://doi.org/10.1021/acs.est.4c10595 PMID: 398893674 PMCID: PMC11823446
DOI: https://doi.org/10.22427/NTP-DATA-500-017-001-000-4
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C06100) of Perfluorohexane sulfonate potassium salt (PFHSKslt) (3871-99-6) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (67 kB)
- E03 - Growth Curves (368 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (29 kB)
- P04 - Neoplasms by Individual Animal (215 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (217 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (75 kB)
- P11 - Statistical Analysis of Survival Data (28 kB)
- P14 - Individual Animal Pathology Data (276 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (216 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30 kB)
- P40 - Survival Curves (427 kB)
- PA06 - Organ Weights Summary Females (71 kB)
- PA06 - Organ Weights Summary Males (71 kB)
- PA41 - Clinical Chemistry Summary Females (164 kB)
- PA41 - Clinical Chemistry Summary Males (164 kB)
- PA43 - Hematology Summary Females (149 kB)
- PA43 - Hematology Summary Males (148 kB)
- PA45 - Liver Special Studies Summary (36 kB)
- PA48 - Summary of Tissue Concentration Males (54 kB)
- PA48 - Summary of Tissue Concentration Females (42 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary Females (45 kB)
- R07 - Hormone Summary Males (46 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (44 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (20 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data Females (10 kB)
- Individual Animal Clinical Chemistry Data Males (11 kB)
- Individual Animal Hematology Data Females (12 kB)
- Individual Animal Hematology Data Males (12 kB)
- Individual Animal Hormone Data Females (8 kB)
- Individual Animal Hormone Data Males (8 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data Females (9 kB)
- Individual Animal Organ Weight Data Males (10 kB)
- Individual Animal Tissue Concentration Data Females (7 kB)
- Individual Animal Tissue Concentration Data Males (7 kB)
- Individual Vaginal Cytology Data (25 kB)
- Individual_Animal_PCR_Data (24 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (35 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (2 kB)